Early manifestations of gastric cancer

Written by Liu Liang
Oncology
Updated on September 05, 2024
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The early signs of gastric cancer may include nausea, vomiting, or mild acid reflux, which are symptoms similar to those of gastritis, stomach ulcers, or duodenal ulcers. Therefore, initially, these patients may not take their condition seriously, assuming they might just have gastritis or peptic ulcers. These are some of the early manifestations of gastric cancer, and some patients may also experience discomfort and a feeling of fullness after eating.

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Late-stage symptoms of gastric cancer

The common late-stage symptoms of gastric cancer patients include nausea, vomiting, and even a complete inability to eat. There are also symptoms related to the digestive tract such as pain in the upper abdomen and acid reflux, as well as upper gastrointestinal bleeding, such as vomiting blood and melena which are signs of lower gastrointestinal bleeding. Late-stage gastric cancer patients may also experience organ metastasis, leading to corresponding symptoms. For example, metastasis of gastric cancer to the liver can cause abdominal pain and ascites due to hepatic metastatic tumors. Clinical manifestations caused by such metastatic tumors also include metastasis to retroperitoneal lymph nodes in the abdominal cavity, a common site of spread for gastric cancer. Patients may even show symptoms of intestinal obstruction, such as abdominal pain, bloating, nausea, vomiting, inability to pass stool, or even absence of flatus, which are indicators of intestinal obstruction. Consequently, patients might experience weight loss and deteriorate into a cachectic state, marked by poor nutrition and significant weight loss, which are characteristic symptoms of late-stage patients.

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Oncology
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early symptoms of gastric cancer

The early symptoms of gastric cancer are similar to those of some gastrointestinal diseases such as gastritis, gastric ulcers, or duodenal ulcers. They don't have very specific clinical manifestations. Common symptoms include nausea, vomiting, discomfort or pain in the upper abdomen, and acid reflux-like symptoms, which are early symptoms in patients with gastric cancer. Therefore, when such symptoms appear, it is essential to seek medical attention promptly and undergo a thorough gastroscopy.

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Symptoms of gastric cancer

Symptoms of gastric cancer include nausea, vomiting, acid reflux, pain in the upper abdomen, and a sense of fullness and discomfort, especially after eating, which are some of the early symptoms. As the tumor progresses, symptoms can worsen, including pain, vomiting of blood, and black stools indicating upper gastrointestinal bleeding. If the tumor is near the pylorus, it can cause pyloric obstruction, which manifests as acid reflux followed by vomiting of undigested food from the previous night. In the late stages of gastric cancer, patients may experience fatigue, weight loss, severe cachexia, and anemia. These are symptoms of advanced gastric cancer.

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How to check for gastric cancer?

Gastroscopy is very important in the examination of gastric cancer, and taking a biopsy under gastroscopy is an important means of diagnosis. Other examinations include endoscopic ultrasound or enhanced abdominal CT and chest CT to assess the staging of the patient. With endoscopic ultrasound, we can see which layer of the stomach wall the tumor has invaded and then combine it with chest and abdominal CT scans to assess whether there is distant metastasis. Diagnosis requires gastroscopy with a biopsy taken during the procedure.

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Oncology
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How is gastric cancer caused?

The causes of gastric cancer are not yet clearly understood. However, its occurrence is associated with poor dietary habits, such as irregular eating—sometimes skipping a meal, sometimes overeating, not having meals on time—and consuming pickled food, barbecued junk food, and other unhealthy dietary practices. Additionally, smoking, alcohol consumption, infection with Helicobacter pylori, chronic gastric diseases such as atrophic gastritis, and genetic factors are all somewhat related to the development of this condition.