Dementia

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Written by Zhang Hui
Neurology
1min 29sec home-news-image

Symptoms of dementia in the elderly

Dementia in the elderly is medically known as Alzheimer's disease, which is categorized into mild, moderate, and severe stages. The clinical manifestations vary with the severity of the disease. Mild dementia primarily presents as memory impairment, starting with a decline in short-term memory, where patients often forget daily activities. For instance, they might forget the way home when they go out, forget to add salt when cooking, or forget to turn off the stove. Patients may also exhibit personality disorders, such as neglecting personal hygiene or not wanting to bathe. As the disease progresses to moderate dementia, besides worsening memory impairment, the patient's ability to work, learn new knowledge, and communicate with others significantly diminishes. There is a notable decline in previously acquired knowledge and skills, such as judgment and calculation abilities. They may also experience aphasia, apraxia, agnosia, and some patients may exhibit significant behavioral and psychological abnormalities. With further progression to severe dementia, patients may become emotionally detached, exhibit unpredictable crying or laughing, fail to recognize family members, lose verbal abilities, and even become unable to perform simple tasks such as dressing or eating. They may spend their days in bed, not speaking, and gradually lose contact with the outside world, ultimately leading to death.

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Written by Tang Bo
Neurology
1min home-news-image

How long is the lifespan of someone with Alzheimer's?

The causes of dementia in the elderly can be varied, with many diseases such as Alzheimer's disease, Parkinson's disease, and vascular dementia, all leading to senile dementia. Therefore, how long one lives may require specific analysis. If the dementia is due to cerebrovascular factors, the lifespan of the individual may be closely related to the primary disease, i.e., cerebrovascular disease. Dementia caused by Alzheimer's disease progresses with the disease and affects the patient's lifespan. In its advanced stages, when the patient can no longer take care of themselves, complications such as lung infections can further impact their lifespan. There are also other factors, which need to be assessed based on the evaluation of the disease.

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Written by Zhang Hui
Neurology
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Determination of Senile Dementia

The assessment of dementia primarily encompasses three aspects: The first aspect mainly involves relevant neurological scales, which can scientifically and effectively measure the cognitive functions of elderly patients. These scales include the MSE (Mini-Mental State Examination) and the MoCA (Montreal Cognitive Assessment). The second aspect of the assessment involves some imaging tests, mainly cranial MRI scans. Cranial MRI can determine if there is brain atrophy in the elderly and examine for any related lesions in the temporal lobes and hippocampi. The third major aspect involves the analysis of cerebrospinal fluid, assessing the levels of amyloid proteins, which also play an important role in the assessment of dementia. In summary, the assessment of dementia primarily involves evaluations using neurological scales, cranial MRI, and cerebrospinal fluid analysis.

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Written by Zhang Hui
Neurology
1min 10sec home-news-image

How is Alzheimer's disease treated?

Senile dementia, also known as Alzheimer's disease, is the most common neurodegenerative disease worldwide. The pathogenesis of this disease is not particularly clear so far and may be related to genetic and environmental factors. Multiple factors act on neurons causing irreversible and progressive death of neuronal cells. Currently, the treatment of this disease mainly includes two aspects. The first aspect is general treatment, mainly including family care. Family members must pay attention to the care of the patient, prevent the patient from accidentally wandering off, prevent the patient from falling, and prevent some accidents that cause injuries. In addition, it is important for the patient to listen to music, interact with others, and exercise more, all of which can delay the progression of senile dementia. The second aspect is pharmacological treatment, mainly using drugs that inhibit the reduction of acetylcholine. These drugs can increase the content of acetylcholine and improve the cognitive functions of patients to a certain extent, but so far, these treatments cannot reverse senile dementia.

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Written by Zhang Hui
Neurology
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early signs of dementia

Dementia in the elderly, mainly referring to Alzheimer's disease, is primarily characterized by a significant decline in the patient's memory and learning abilities. Of course, there are some prodromal symptoms before the onset of dementia. For example, patients might show no clinical signs of cognitive impairment or only display very slight memory decline. Patients might exhibit mild impairment in memory, a decrease in the ability to learn and retain new information, and mild impairments in other cognitive areas such as attention, executive function, language skills, and visuospatial abilities. However, these impairments are very slight and can go unnoticed by family members. Moreover, these mild impairments do not affect the patient's basic daily life abilities and do not reach the level of dementia. Patients can live independently and manage their routine daily tasks, which are mainly some of the early signs of dementia.

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Written by Zhang Hui
Neurology
1min 9sec home-news-image

Causes of Alzheimer's Disease in the Elderly

The causes of dementia in the elderly are not currently completely clear. Dementia in the elderly is mainly divided into familial and sporadic types. Familial dementia shows autosomal dominant inheritance, which is caused by a gene mutation on chromosome 21 leading to the accumulation of some toxins, resulting in the death of neurons and causing dementia fundamentally due to genetic mutations. However, most cases of dementia are sporadic and do not have a clear family history. The mechanisms and reasons for disease onset are not particularly clear. Some believe that abnormalities in cerebral vascular function may lead to neuronal cell functional disorders, resulting in decreased ability to clear certain cell toxins, thus leading to neuronal apoptosis and death, and consequently impaired cognitive functions. In addition, factors such as oxidative stress, inflammatory mechanisms, excessive fatigue, and emergency stress may also cause cell death. Overall, the causes of dementia in the elderly are not particularly clear.

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Written by Tang Bo
Neurology
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What is dementia called?

The commonly mentioned senile dementia, also known as Alzheimer's disease, is the most common type of dementia. Its incidence generally increases in people over the age of 65 and continues to increase with age. It is a degenerative disease, with risk factors including age and gender, usually higher in women than in men. It is also related to educational level, whether there has been trauma, genetics, thyroid function, exposure to toxic substances, as well as vascular factors. Diabetes and depression are also risk factors for senile dementia.

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Written by Zhang Hui
Neurology
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precursors of senile dementia

The diagnosis of senile dementia must first meet the diagnostic criteria for dementia, primarily characterized by impairment in multiple cognitive areas such as memory, language skills, executive function, and computational ability, and these impairments affect daily life; this is called senile dementia. Before dementia occurs, there are some precursory signs, mainly slight declines in memory. For example, patients might occasionally forget to bring keys when going out, or forget to turn off the stove while cooking. These mild memory impairments are some of the precursors to senile dementia. Additionally, there is a decline in learning ability, including the symptoms of learning new knowledge and mastering new skills; these declines are also precursors to senile dementia. Therefore, the precursors of senile dementia can primarily be summarized as a slight decline in memory function and some slight decline in learning ability.

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Written by Tang Bo
Neurology
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Mild manifestations of senile dementia

Mild dementia, especially in its early stages, often goes unnoticed by family members. The initial symptoms generally include being particularly forgetful. This particularly affects short-term memory; for example, a person might repeat what was just said or be repeatedly clumsy in daily tasks, sometimes losing keys or forgetting to turn off the stove while cooking. This might seem like a lack of concentration, but in reality, it is due to forgetfulness. Emotionally, individuals who were once lively might become indifferent or detached, sometimes showing signs of excitement or agitation. Behaviorally, there can be changes, such as previously generous individuals becoming stingy. Interests and hobbies that were once loved may no longer hold appeal, and individuals may become lethargic and less concerned with cleanliness and personal appearance.

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Written by Zhang Hui
Neurology
1min 2sec home-news-image

symptoms of dementia in the elderly

The symptoms of dementia mainly include: First, impaired memory function, where the patient’s memory loss is very noticeable. Initially, they may not remember recent events, and as the disease progresses, they may not remember past events, such as forgetting how many children they have or their children’s names. Second, it mainly involves symptoms of impairment in other cognitive areas, such as visual spatial dysfunction, manifesting as not being able to find the bathroom at home, getting lost after going out, and not being able to find the way back home. Additionally, the patient's ability to understand, calculate, and judge will also be significantly impaired, and they cannot master previously learned knowledge and skills. Third, in the late stages, some psychiatric symptoms appear, including visual and auditory hallucinations, and agitated behaviors such as hitting and cursing. Additionally, the patient may also experience some physical weakness, muscle atrophy, and incontinence.