Cor pulmonale refers to a disease characterized by increased pulmonary vascular resistance due to pathologies of the bronchi, lung tissue, chest wall, and blood vessels of the lungs, leading to pulmonary arterial hypertension and structural and functional changes in the right ventricle. The common clinical symptoms of cor pulmonale include coughing, expectoration, shortness of breath, significant palpitations, and breathing difficulties after physical activity, reduced work capacity, and exacerbation of the above symptoms during acute infection phases. Some patients may experience chest pain and hemoptysis. The second set of symptoms relates to heart and lung function, manifesting during the decompensation phase. For instance, some patients may develop respiratory failure, and experience headaches, decreased appetite, drowsiness, significant edema in the lower extremities, and further symptoms such as arrhythmias, anorexia, abdominal distension, and nausea.