Heart disease, such as coronary atherosclerotic heart disease, can potentially cause numbness in the hands. When angina or myocardial infarction of coronary heart disease occurs, there is often severe chest pain. This chest pain may be accompanied by pain and numbness in the left shoulder or left hand. During episodes of pain, an electrocardiogram often shows significant ST depression or ST elevation. This condition is commonly seen in middle-aged and elderly patients. In addition, cervical spondylosis can also cause numbness in the hands, often seen in young people who spend long periods looking down at their mobile phones or using computers, usually showing symptoms of neck pain. A cervical spine MRI can often determine whether cervical spondylosis is causing these symptoms.