Patients with depression may occasionally feel happy, but they predominantly experience low mood throughout most of their days. Patients perceive a significant and persistent sense of low spirits, pessimism, and despair. Their mood is such that they cannot feel joy, and they often seem easy to recognize by their facial expressions – furrowed brows, frowning, and looking deeply worried. Thus, these patients feel downhearted; nothing seems to interest them, they feel as if something heavy is pressing on their heart, devoid of pleasure, often crying, pessimistic, despairing, feeling as if each day lasts a year, and life not worth living. Sometimes, patients may feel that life is meaningless, hence might engage in self-harming or suicidal behaviors, blame themselves harshly, and have trouble concentrating. However, it's not that patients never experience happiness; it's just that they are in a depressed mood most of the time each day, with only occasional moments of happiness, which are relatively rare.