Systemic lupus erythematosus is a chronic autoimmune disease causing multi-system damage, with clinical presentations that vary greatly between individuals. Most cases begin gradually, but some can onset abruptly, meaning severe complications that can threaten life can emerge within weeks or days. Early symptoms are often atypical. During active phases, most patients with systemic lupus erythematosus experience varying degrees of low-grade fever, with low to moderate fevers being most common. The primary manifestations include erythema of the skin and mucous membranes, and some individuals may experience photosensitivity, which results in a facial rash after exposure to sunlight. This is one of the most common clinical presentations.