Rheumatoid arthritis skin manifestations

Written by Liu Li Ning
Rheumatology
Updated on February 25, 2025
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Rheumatoid arthritis does not have specific skin manifestations. Rheumatoid arthritis is an immune-mediated erosive arthritis, clinically characterized by systemic symmetrical multiple joint swelling and pain, accompanied by morning stiffness, often lasting for more than an hour. Rheumatoid arthritis can affect the proximal interphalangeal joints and middle joints of both hands, as well as both wrists, elbows, shoulders, ankles, knees, and other joints. Some patients may experience involvement of the temporomandibular joint. Rheumatoid arthritis can also have extrarticular manifestations, such as affecting the hematological system, which may result in mild to moderate anemia, or affecting the lungs, which can lead to interstitial pneumonia or pulmonary fibrosis.

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Written by Yang Ya Meng
Rheumatology
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Rheumatoid Arthritis Diagnostic Criteria

The diagnostic criteria for rheumatoid arthritis include the following aspects: The first is symmetrical joint pain, primarily characterized by tenderness and swelling in the metacarpophalangeal joints, proximal interphalangeal joints, and both wrists. Secondly, it also includes abnormalities in inflammation markers, which comprise erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), along with abnormalities in certain antibodies, mainly rheumatoid factor, CCP antibodies, and AKA antibodies. If the above symptoms are present, and these inflammation markers and antibodies are found to be abnormal upon blood testing, a diagnosis of rheumatoid arthritis can be made.

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Written by Liu Li Ning
Rheumatology
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How is rheumatoid arthritis treated?

The treatment of rheumatoid arthritis is divided into general treatment and pharmacological treatment. General treatment mainly involves avoiding overexertion, having a light diet, and not staying up late. Pharmacological treatment is mainly divided into treatment during the acute flare-up phase and the remission phase. The acute phase focuses on anti-inflammatory and pain relief treatments, with non-steroidal anti-inflammatory drugs (NSAIDs) as the first choice, such as etoricoxib, meloxicam, or celecoxib. If the effect is not satisfactory, low-dose corticosteroid therapy may be combined. In the remission phase, slow-acting anti-rheumatic drugs are preferred, such as methotrexate, leflunomide, or sulfasalazine. If the slow-acting anti-rheumatic drugs are not effective, biologic agents such as tumor necrosis factor antagonists or JAK inhibitors may be combined.

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Written by Li Jing
Rheumatology
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Does rheumatoid arthritis hurt?

Firstly, rheumatoid arthritis belongs to autoimmune diseases and is a chronic condition. The main symptoms include symmetric pain in multiple joints across the body, accompanied by morning stiffness, which is why joint pain occurs and is the most common symptom. The onset is slow for most people, but some experience an acute onset, with joint mobility issues appearing within a few weeks or days. Therefore, this disease cannot be cured; it can only be managed with medications to control symptoms, delay the deformity of joints, reduce disability rates, and enhance the quality of life, which are the objectives of comprehensive treatment. It is important to avoid exposure to cold and fatigue in daily life, avoid contact with cold water, keep warm, also avoid raw and cold foods, spicy and irritating foods, and eat more light, easy-to-digest, and high-protein foods to boost the immune system.

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Orthopedic Surgery
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Rheumatoid arthritis is what's going on?

Rheumatoid arthritis is a chronic systemic disease of unknown etiology characterized primarily by inflammatory synovitis. Its main features are aggressive joint inflammation that symmetrically affects multiple small joints of the hands and feet. It often accompanies involvement of extra-articular organs and a positive rheumatoid factor in serum. It can ultimately lead to joint deformity and loss of function. The onset of the disease may be related to genetic, infectious, and hormonal factors.

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Written by Li Jie
Orthopedics
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The difference between osteoarthritis and rheumatoid arthritis

In everyday life, many patients confuse osteoarthritis with rheumatoid arthritis, but these two diseases are indeed very distinct. Generally speaking, osteoarthritis is mostly caused by hyperplastic arthritis due to trauma or, in some cases, osteoarthritis resulting from overuse, The characteristic of osteoarthritic pain is that it is related to activity. The more a joint affected by arthritis moves, and the greater the overuse, the more severe the pain becomes. When resting, the pain in that joint will decrease, However, rheumatoid arthritis is different and has clear distinctions from osteoarthritis. Rheumatoid arthritis typically affects the small joints of the limbs, usually occurs symmetrically, and rarely affects only one limb. Once it occurs, it generally affects other parts too, appearing in both hands or both feet. These small joints are usually the first to be affected, with symptoms presenting symmetrically, and there is significant morning stiffness; that is, joints are stiff in the morning, Furthermore, rheumatoid arthritis can cause pain at rest or pain during inactivity, and nocturnal pain does not necessarily correlate with activity. Sometimes, pain may intensify after rest or during the night, and sometimes, physical activity may actually alleviate the pain. Thus, this symptom is a primary distinguishing feature from osteoarthritis. Understanding these points, the differences between osteoarthritis and rheumatoid arthritis can basically be mastered.