The difference between osteoarthritis and rheumatoid arthritis

Written by Li Jie
Orthopedics
Updated on September 02, 2024
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In everyday life, many patients confuse osteoarthritis with rheumatoid arthritis, but these two diseases are indeed very distinct. Generally speaking, osteoarthritis is mostly caused by hyperplastic arthritis due to trauma or, in some cases, osteoarthritis resulting from overuse,

The characteristic of osteoarthritic pain is that it is related to activity. The more a joint affected by arthritis moves, and the greater the overuse, the more severe the pain becomes. When resting, the pain in that joint will decrease,

However, rheumatoid arthritis is different and has clear distinctions from osteoarthritis. Rheumatoid arthritis typically affects the small joints of the limbs, usually occurs symmetrically, and rarely affects only one limb. Once it occurs, it generally affects other parts too, appearing in both hands or both feet. These small joints are usually the first to be affected, with symptoms presenting symmetrically, and there is significant morning stiffness; that is, joints are stiff in the morning,

Furthermore, rheumatoid arthritis can cause pain at rest or pain during inactivity, and nocturnal pain does not necessarily correlate with activity. Sometimes, pain may intensify after rest or during the night, and sometimes, physical activity may actually alleviate the pain. Thus, this symptom is a primary distinguishing feature from osteoarthritis. Understanding these points, the differences between osteoarthritis and rheumatoid arthritis can basically be mastered.

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Written by Yang Ya Meng
Rheumatology
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What causes rheumatoid arthritis?

The causes of rheumatoid arthritis are mainly classified into four categories, First, environmental factors, such as living in dark, damp conditions for a long period, may trigger the onset of rheumatoid arthritis. Second, genetic factors, the probability of developing rheumatoid arthritis significantly increases if a parent has the condition. Third, rheumatoid arthritis often relates to estrogen, thus it is more commonly seen in female patients clinically. Fourth, rheumatoid arthritis is also associated with certain infections, including some viral and bacterial infections.

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Written by Yang Ya Meng
Rheumatology
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How is rheumatoid arthritis diagnosed?

Rheumatoid arthritis examinations include blood tests and imaging studies. The blood tests include complete blood count, erythrocyte sedimentation rate, rheumatoid factor, C-reactive protein, anti-streptococcal antibodies, ANA, anti-CCP antibodies, and anti-AKA antibodies. Imaging studies involve X-ray examinations of the hand joints. If the patient has significant increases in erythrocyte sedimentation rate and C-reactive protein, positive CCP and AKA antibodies, and the X-rays show bone destruction, then rheumatoid arthritis can be considered as a diagnosis.

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Written by Cheng Bin
Orthopedics
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Is joint pain rheumatoid arthritis?

Firstly, it should be noted that there are many causes of joint pain in clinical practice, and it is not necessarily caused by rheumatoid arthritis. Of course, rheumatoid arthritis can also cause joint pain in patients. In addition, there are some other reasons, for example, local joint bacterial infection in patients can also cause joint pain. Furthermore, joint injuries leading to fractures, dislocations, soft tissue damage, ligament injuries, and meniscus injuries can also cause joint pain. Additionally, the presence of osteoarthritis or gouty arthritis can similarly lead to joint pain in patients.

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Written by Yang Ya Meng
Rheumatology
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Is rheumatoid arthritis serious?

Patients with rheumatoid arthritis, if treated reasonably and formally, can achieve clinical remission, so in this sense, rheumatoid arthritis is not severe. However, if patients do not adhere to formal treatment for a long time, after a long period, they may develop joint deformities and ankylosis, resulting in disability. From this perspective, rheumatoid arthritis should be taken seriously. Commonly used drugs for treating rheumatoid arthritis include anti-inflammatory pain relievers, with non-steroidal pain relievers being the most commonly used, such as sustained-release diclofenac sodium tablets. The most important step in treating rheumatoid arthritis is the selection of immunosuppressants, with common immunosuppressants including methotrexate and leflunomide. (Medication should be used under the guidance of a doctor based on specific circumstances.)

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Written by Li Jing
Rheumatology
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Does rheumatoid arthritis cause fever?

Rheumatoid arthritis is categorized as an autoimmune disease, primarily characterized by swelling and pain in multiple joints, particularly in the wrists or ankles. It also causes morning stiffness, and may be accompanied by fatigue, low fever, muscle soreness, and even weight loss. The onset of the disease is generally gradual for most people, and symptoms can vary significantly from one individual to another. A minority of patients may experience a rapid onset of symptoms, developing joint problems within days or weeks. Therefore, during the acute phase of rheumatoid arthritis, patients may experience a mild or moderate fever. However, it is important to differentiate whether this fever is due to an infection or the activity of the disease itself. This can be determined through regular blood tests, erythrocyte sedimentation rate (ESR), C-reactive protein, and related symptoms.