Rheumatoid arthritis is what's going on?

Written by Chen Hui
Orthopedic Surgery
Updated on September 25, 2024
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Rheumatoid arthritis is a chronic systemic disease of unknown etiology characterized primarily by inflammatory synovitis. Its main features are aggressive joint inflammation that symmetrically affects multiple small joints of the hands and feet. It often accompanies involvement of extra-articular organs and a positive rheumatoid factor in serum. It can ultimately lead to joint deformity and loss of function. The onset of the disease may be related to genetic, infectious, and hormonal factors.

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Written by Yang Ya Meng
Rheumatology
51sec home-news-image

What medicine is taken for rheumatoid arthritis?

The medication for rheumatoid arthritis mainly falls into three categories, The first category is the choice of anti-inflammatory and pain relief medications, which mainly includes two types: non-steroidal analgesics and low doses of corticosteroids. If the patient's pain symptoms are mild, non-steroidal analgesics can be opted for. However, if the patient's pain symptoms are more severe, and there is significant liver or kidney damage, or concurrent interstitial lung disease, then the use of low doses of corticosteroids should be considered. The second and most important category is the choice of immunosuppressants, which include drugs like methotrexate and leflunomide. The third category is the treatment with biologic agents. (Medication should be administered under the guidance of a doctor)

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Written by Liu Li Ning
Rheumatology
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How should rheumatoid arthritis be treated?

The treatment of rheumatoid arthritis includes several aspects. First, general treatment: keep a light diet, avoid spicy and stimulant foods, ensure joints are kept warm, and avoid excessive fatigue. Second, medication treatment: during acute flare-ups, non-steroidal anti-inflammatory drugs such as diclofenac sodium or etoricoxib can be used, possibly combined with low doses of corticosteroids. During stable phases, immunosuppressants such as methotrexate or leflunomide are needed. If conventional treatments are ineffective, biological agents like adalimumab or tofacitinib can be combined. Most patients can effectively control their condition after combined treatment. Third, traditional Chinese medicine: alongside Western medicine, Chinese herbal medicine such as total glucosides of paeony or tripterygium wilfordii polyglycoside can be used.

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Written by Yang Ya Meng
Rheumatology
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Characteristics of rheumatoid arthritis in the hand

The key hand features of rheumatoid arthritis primarily manifest as symmetrical joint swelling and pain in both hands in the early stages. These swollen and painful joints include both wrist joints, bilateral metacarpophalangeal joints, and bilateral proximal interphalangeal joints. Rheumatoid arthritis rarely affects the distal interphalangeal joints of the hands. In the later stages of rheumatoid arthritis, due to the destruction of the hand joints by synovitis, some patients may develop deformities in the hand joints, commonly including ulnar deviation, swan neck deformities, or boutonniere deformities. Some patients may experience significant stiffness leading to limited mobility of the hand joints.

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Written by Li Jie
Orthopedics
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How to treat rheumatoid arthritis?

Rheumatoid arthritis-induced joint pain has several distinct characteristics: The first is that it initially affects the small joints of the limbs, typically involving the hands, feet, wrists, and ankles, before spreading to larger joints. It rarely starts in the large joints first. Secondly, the onset is generally symmetrical, meaning it seldom affects just a single limb or joint. Typically, if the disease manifests, it affects both limbs simultaneously. Another characteristic is significant morning stiffness, meaning a feeling of stiffness upon waking up in the morning. Generally, by combining auxiliary tests such as blood tests and imaging, a clear diagnosis of rheumatoid arthritis can be made. Once diagnosed, it is advised that patients seek treatment at a reputable hospital in the rheumatology and immunology department or orthopedics, targeting specific treatments and avoiding unlicensed practitioners. Common rheumatoid arthritis treatment plans start with medications to alleviate symptoms, using immunosuppressants. In severe cases, a small, short-term dose of steroids may be used. Additionally, symptomatic treatment may include topical applications of ointments to improve blood circulation, reduce swelling, and alleviate pain. Patients can also take non-steroidal anti-inflammatory drugs orally to relieve symptoms. Furthermore, traditional Chinese medicine is also a very effective method, and patients can take specific herbal medicines as symptomatic treatment for rheumatic joint pain, which are also very effective. (Please follow a professional physician's guidance when using medications and do not medicate blindly.)

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Written by Yang Ya Meng
Rheumatology
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The difference between osteoarthritis and rheumatoid arthritis.

Osteoarthritis is primarily a degenerative joint disease, most commonly occurring in weight-bearing joints and the distal joints of both hands. Therefore, if there is pain in the distal joints of the hands or in joints like the knee, it may be osteoarthritis. Rheumatoid arthritis mainly affects the metacarpophalangeal joints, proximal interphalangeal joints, and both wrists. It is also important to distinguish that in patients with osteoarthritis, inflammation indicators such as sedimentation rate, C-reactive protein, and endocrine factors are usually normal. However, in patients with rheumatoid arthritis, these indicators, including sedimentation rate, C-reactive protein, and rheumatoid factor, are abnormally elevated.