Early symptoms of ankylosing spondylitis

Written by Sun Shu Jian
Orthopedics
Updated on January 13, 2025
00:00
00:00

The early symptoms of ankylosing spondylitis mainly include insidious onset of pain and discomfort in the back and hip joints.

The pain is often intermittent and worse at night. Patients frequently wake up at night due to back pain, which can be alleviated by slight movement. Therefore, when patients experience unexplained back and hip joint pain, it is necessary to determine whether ankylosing spondylitis could be a possibility.

In the early stages, a sacroiliac joint CT scan and hematological examination can be performed to confirm the diagnosis. Once diagnosed, prompt standardized treatment is necessary. Generally, this can control synovial inflammation and pain, prevent deformities of the spine and joints, and help patients return to normal life and work.

Other Voices

doctor image
home-news-image
Written by Yang Ya Meng
Rheumatology
49sec home-news-image

How to control ankylosing spondylitis

The treatment of ankylosing spondylitis mainly consists of three parts: The first part is the use of non-steroidal anti-inflammatory drugs, such as sustained-release diclofenac sodium tablets; the second is the choice of disease control medications, which may include sulfasalazine or methotrexate tablets, especially for patients with peripheral joint pain, immunosuppressive drugs can be chosen. The most effective for ankylosing spondylitis are biologics, but before using biologics, it is necessary to exclude hepatitis, tuberculosis, and cancerous diseases, and the cost of biologics is relatively high. (Please use medications under the guidance of a professional physician and do not self-medicate.)

doctor image
home-news-image
Written by Li Jing
Rheumatology
47sec home-news-image

What should I do in the late stage of ankylosing spondylitis?

Firstly, ankylosing spondylitis is an autoimmune disease primarily affecting the axial joints, but it can also present with extra-articular manifestations. Severe cases can lead to ankylosis and deformities of the spine, which are complications of late-stage ankylosing spondylitis. At this stage, surgery is needed to manage the activity of the disease. If the activity of the disease is not controlled, even joint replacement can still lead to the progression of the disease and further damage to the joint structures. For severe disabling deformities, spinal orthopedic surgery can be considered, and spinal surgery is required when an acute fracture occurs.

doctor image
home-news-image
Written by Li Jing
Rheumatology
58sec home-news-image

What causes ankylosing spondylitis?

Ankylosing spondylitis is primarily an autoimmune disease affecting the axial joints, which may also manifest with extra-articular symptoms. In severe cases, deformities and stiffening of the spine can occur. The cause of the disease is attributed to the interactive effects of genetics and environmental factors, making it a multi-gene inherited disorder. However, for some individuals, it may also be related to infections such as Ureaplasma urealyticum, Shigella, Salmonella, and Escherichia coli in the urinary and genital tracts. These pathogens trigger the body's inflammatory immune response, resulting in tissue damage and contributing to the onset and progression of the disease. There is a notable familial aggregation in the occurrence of this disease.

doctor image
home-news-image
Written by Li Jing
Rheumatology
55sec home-news-image

Ankylosing Spondylitis Exercise Methods

Ankylosing spondylitis is an autoimmune disease that primarily affects the axial joints and currently has no curative treatment. Its treatment includes general measures, medication, and surgery. General measures mainly involve abstaining from alcohol, quitting smoking, avoiding carbonated drinks and coffee, which can lead to osteoporosis. In addition, it is important to focus on exercise; functional exercises are a crucial part of its treatment. Regular activities such as swimming, walking, and running are recommended, and chest-expanding exercises can improve muscle rigidity. Moreover, it is advisable to sleep on a hard bed to keep the spine level. Swimming is the best form of exercise for patients with ankylosing spondylitis as it does not overload the joints while also enhancing the coordination and flexibility of the limb muscles.

doctor image
home-news-image
Written by Na Hong Wei
Orthopedics
1min 34sec home-news-image

What is Ankylosing Spondylitis?

Ankylosing Spondylitis (AS), where "A" stands for fusion and "S" for spine, refers to the condition where the bones and joints of the spine are fused together. Ankylosing Spondylitis is defined as a chronic inflammatory disease primarily affecting the axial skeleton and major limb joints. It is characterized by fibrosis and ossification of the intervertebral discs’ annulus fibrosus and nearby connective tissues, as well as ankylosis (stiffening) of the joints. It presents as a sterile inflammation occurring in the spine. However, it is not solely limited to the spine as it also involves the axial bones and major limb joints. The pathological hallmark of the disease includes inflammation mainly at the sacroiliac joints and points of attachment to the spine, leading to joint stiffness and calcification of the spinal ligaments and joints. The disease progression begins at the sacroiliac joint, spreading upwards through the entirety of the spine, and eventually stops at the cervical vertebrae. Symptoms start with pain in the early stages, followed by restricted mobility in the intermediate phase, and ultimately leading to deformities of the abdomen and back, culminating in severe hunchback. The exact cause of Ankylosing Spondylitis remains unclear, with various theories proposed but none universally accepted. Additionally, it is categorized under rheumatologic and immunologic disorders.