Can ankylosing spondylitis be cured?

Written by Na Hong Wei
Orthopedics
Updated on September 26, 2024
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Based on the current situation, it is very difficult to cure ankylosing spondylitis. Ankylosing spondylitis is a chronic disease primarily affecting the spine. It mainly involves the sacroiliac joints and spine, eventually causing spinal stiffness and restricted movement. Additionally, it can cause varying degrees of damage to multiple organs such as the eyes, lungs, cardiovascular system, and kidneys.

Ankylosing spondylitis is commonly referred to as AS, where 'A' stands for fusion and 'S' for spine, hence the term means spinal fusion. Currently, the cause of the disease is unknown, and there are no specific clinical treatments. The basic treatment principle involves alleviating pain, preventing spinal deformities, and strengthening the back muscles. Typically, conservative treatment is used during the early or middle stages, while surgical correction may be considered in the later stages when significant spinal deformities occur. Generally, ankylosing spondylitis is very difficult to cure.

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Written by Li Jing
Rheumatology
49sec home-news-image

Does ankylosing spondylitis hurt?

Ankylosing spondylitis primarily targets the axial joints, manifesting as a chronic autoimmune disease. The most common clinical symptoms include stiffness in the neck and pain in the lumbar and back regions, areas particularly associated with axial joint involvement, predominantly affecting the spine. Additionally, symptoms can also appear in areas outside of the joints, such as pain in the peripheral joints, heels, wrists, and shoulders. Moreover, some individuals may experience eye inflammation, including recurrent uveitis and corneal ulcers. While spinal pain, neck stiffness, and lumbar or back pain are the most commonly observed clinical manifestations, hip joint pain is also frequently noted.

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Written by Yang Ya Meng
Rheumatology
1min 7sec home-news-image

How is ankylosing spondylitis treated?

The treatment of ankylosing spondylitis mainly consists of three parts: The first part is anti-inflammatory and pain relief. For anti-inflammatory pain relief, non-steroidal pain relief medications are commonly chosen, such as slow-release diclofenac sodium tablets and celecoxib capsules. The second part involves the selection of medications to control the disease. Common drugs used to control the condition include sulfasalazine, thalidomide, and methotrexate tablets. The third part includes the most effective, yet most expensive, treatment option: biological agents. Common biological agents used are tumor necrosis factor antagonists. However, before using biological agents, strict screening for diseases such as hepatitis, tuberculosis, and cancer is required. Only after excluding these conditions can the treatment with biological agents be considered.

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Written by Na Hong Wei
Orthopedics
1min 11sec home-news-image

Can ankylosing spondylitis be cured?

Based on the current situation, it is very difficult to cure ankylosing spondylitis. Ankylosing spondylitis is a chronic disease primarily affecting the spine. It mainly involves the sacroiliac joints and spine, eventually causing spinal stiffness and restricted movement. Additionally, it can cause varying degrees of damage to multiple organs such as the eyes, lungs, cardiovascular system, and kidneys. Ankylosing spondylitis is commonly referred to as AS, where 'A' stands for fusion and 'S' for spine, hence the term means spinal fusion. Currently, the cause of the disease is unknown, and there are no specific clinical treatments. The basic treatment principle involves alleviating pain, preventing spinal deformities, and strengthening the back muscles. Typically, conservative treatment is used during the early or middle stages, while surgical correction may be considered in the later stages when significant spinal deformities occur. Generally, ankylosing spondylitis is very difficult to cure.

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home-news-image
Written by Yang Ya Meng
Rheumatology
55sec home-news-image

What to do about ankylosing spondylitis pain?

The methods for treating pain in ankylosing spondylitis primarily include non-steroidal anti-inflammatory drugs, such as sustained-release diclofenac sodium tablets; secondly, biologics can be considered for pain relief, but before using biologics, it is necessary to rigorously rule out diseases such as hepatitis, tuberculosis, and tumors. During the painful periods of ankylosing spondylitis, patients are advised to rest appropriately to alleviate joint inflammation. However, after the pain subsides, it is recommended that patients engage in functional exercises to prevent complications such as further adhesion and stiffening of the spinal joints. (Specific medications should be taken under the guidance of a physician.)

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Written by Li Jing
Rheumatology
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What injections are used for ankylosing spondylitis?

Firstly, ankylosing spondylitis is an autoimmune disease primarily characterized by the destruction of axial joints, a chronic condition that can also manifest peripheral joint lesions. Currently, there are no definitive cures, meaning long-term medication is necessary to alleviate symptoms, control disease progression, delay joint deformity, reduce disability, and improve quality of life. This constitutes the overall goal of treatment. The preferred treatments are non-steroidal anti-inflammatory drugs (NSAIDs) and biologic agents. However, before using biologic agents, it is essential to complete routine blood tests, erythrocyte sedimentation rate, C-reactive protein, screenings for infectious diseases, and tuberculosis. After excluding infections, tuberculosis, and tumors, biologic agents can be administered. During the use of biologic agents, there is a risk of reduced immunity, making it easy to contract infections. Therefore, it is important to avoid getting cold, overwork, and to regularly recheck routine blood parameters, liver, and kidney functions.