What is invasive breast cancer?

Written by Fan Hong Qiao
Breast Health Department
Updated on September 23, 2024
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Invasive breast cancer is the most common tumor in women, accounting for 22% of all malignant tumors in females. Invasive breast cancer refers to a malignant tumor where cancer cells have broken through the basement membrane of the breast ducts or lobular alveoli and invaded the interstitium. The vast majority of invasive breast cancers are adenocarcinomas, originating from the epithelial cells of the breast parenchyma, especially from the terminal duct lobular units. Its characteristics include the tumor's infiltration into adjacent tissues and a marked tendency for distant metastasis.

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Male breast cancer generally occurs at what age?

The general age of onset for male breast cancer is between 65 and 67 years old, which is about five to ten years later than the onset age for female breast cancer. Male breast cancer is a relatively rare malignancy, accounting for only 0.6% to 1% of all breast cancer cases, meaning that out of 100 breast cancer patients, approximately one is male. The development of male breast cancer is caused by multiple factors, which may include genetic factors, environmental influences, and also related to levels of hormone secretion from the endocrine system.

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Clinical manifestations of breast cancer

The clinical manifestations of breast cancer mostly present as painless lumps in the breast. Many early-stage breast lumps are found during physical examinations or screenings. Lumps commonly develop in the upper outer quadrant and are typically solitary on one side, though occasionally there are multiple lumps, or they may appear bilaterally. The size of the clinically observed lumps varies, with diameters of up to 5 centimeters being common. Generally, the lumps are hard in consistency, have unclear boundaries, and are not easily movable within the breast. Sometimes, the nipple may be inverted and there may be bloody discharge. Enlarged lymph nodes may also be present under the armpit.

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Can being angry cause breast cancer?

Frequent anger in women is associated with a higher risk of breast cancer. The causes of breast cancer are not yet fully elucidated, but recent research suggests that its development may be related to various factors. These include familial factors, reproductive factors, levels of sex hormones, and relevant genes. Frequent anger in patients can cause instability in the body's hormones, leading to exacerbated breast hyperplasia. Increased breast hyperplasia can then lead to the formation of small nodules in the breast. Due to the stimulation of estrogen in the body, these breast nodules are more likely to become cancerous. Therefore, it is important to maintain a cheerful mood, minimize anger, and eat more foods containing vitamins, as Vitamin A plays a role in protecting breast cells.

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Breast cancer chemotherapy regimen

Breast cancer chemotherapy regimen. Thus, chemotherapy occupies a very important position in the treatment of breast cancer. The commonly used chemotherapy drugs in breast cancer treatment include alkylating agents, such as cyclophosphamide; antimetabolites like fluorouracil, methotrexate, gemcitabine, and capecitabine; anthracyclines, such as doxorubicin and others. In recent years, taxanes, particularly docetaxel, have been used more frequently. Other drugs include mitomycin and cisplatin, among others. However, the specific chemotherapy regimen for breast cancer should be assessed by a professional oncologist. The regimen should consider the pathological stage, pathological type, whether surgery was performed, whether the surgery completely removed the tumor, lymph node metastasis, and other factors to devise a suitable chemotherapy plan. Therefore, it is possible that each individual might have a regimen that is specifically suited to their situation, and not all regimens are suitable for everyone.

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Early-stage breast cancer symptoms

Early-stage breast cancer may exhibit several symptoms. The first is the presence of breast lumps. The second symptom might be nipple discharge, which can be serous, watery, or milky in nature. The third symptom might involve changes in the skin over the breast tumor, including skin adhesion, such as dimpling, engorgement of superficial veins, skin reddening, localized increase in temperature, and an orange-peel texture. The fourth symptom includes abnormalities of the nipple and areola, potentially featuring nipple retraction, erosion of the nipple, thickening of the nipple epithelium, and reddening. The fifth symptom could be breast pain.