When hypoglycemia occurs, it is possible to experience confusion. This is because, under normal conditions, the glucose level in our brain tissue is only about 25% of that in our blood. After hypoglycemia occurs, the glucose concentration in our brain tissue will further decrease, leading to a state of sugar and oxygen deprivation in the brain. Severe cases can exhibit a range of neuropsychiatric symptoms such as behavioral changes and confusion, cognitive dysfunction, or even epileptic seizures. Some patients may also experience coma and permanent brain damage, typically seen in those with severe and prolonged hypoglycemia. Similarly, patients who repeatedly experience hypoglycemia often also suffer from brain atrophy. Therefore, confusion can occur during hypoglycemia.