After osteoporosis leads to pain, we first need to clarify which part of the body the pain is located, or what causes the pain. If the pain is solely due to osteoporosis, such as decreased bone density in the limbs causing soreness and weakness, it is appropriate to supplement with calcium and vitamin D while also enhancing exercise to alleviate the pain. If the pain is due to fractures caused by osteoporosis, such as vertebral compression fractures or rib fractures, the fractures should first be repositioned, immobilized, and stabilized. Additionally, medications that treat osteoporosis should be used, such as those that inhibit bone resorption and promote bone formation.