Osteoporosis lacks what element?

Written by Lv Yao
Orthopedics
Updated on December 19, 2024
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Osteoporosis refers to a systemic skeletal disease characterized by decreased bone density and strength, resulting in increased bone fragility and potential fractures. There are primarily two types of osteoporosis: primary and secondary. Primary osteoporosis commonly occurs in postmenopausal women and as a result of aging and degenerative changes; secondary osteoporosis sometimes refers to the condition developing after fractures due to prolonged immobilization. Osteoporosis mainly arises from a deficiency in the trace elements calcium and phosphorus, which are crucial components of bone. A lack of these substances can alter bone structure and lead to osteoporosis.

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Written by Lv Yao
Orthopedics
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How to treat osteoporosis?

To address osteoporosis, it's crucial to determine whether it's primary or secondary in origin. For primary osteoporosis, it is advisable to appropriately supplement with calcium and vitamin D to facilitate bone formation and engage in suitable exercise to strengthen the bones. If the osteoporosis is severe, adding medications that promote bone formation and inhibit bone loss can aid in treatment. If a fracture occurs due to osteoporosis, it is first necessary to reposition and stabilize the fracture, while also using medications to prevent further osteoporosis. Osteoporosis caused by long-term immobilization after a fracture can be managed by increasing physical activity, which helps restore blood flow around the fractured area and prevent such osteoporosis.

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Written by Xie Yi Song
Orthopedics
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How is osteoporosis treated?

Osteoporosis is a systemic metabolic disease characterized by low bone mass and destruction of bone tissue microstructure, leading to increased bone fragility and susceptibility to fractures. Osteoporosis is common in the elderly but can occur at any age. Effective pharmacological treatments can prevent and treat osteoporosis, including estrogen replacement therapy, calcitonin, selective estrogen receptor modulators, and bisphosphonates, which can prevent bone resorption but have little effect on bone formation. Medications used to treat and prevent the development of osteoporosis fall into two main categories: the first category includes drugs that inhibit bone resorption, such as calcium supplements, vitamin D and active vitamin D, calcitonin, bisphosphonates, estrogen, and isoflavones; the second category includes drugs that promote bone formation, such as fluoride, synthetic steroids, and isoflavones. In addition to pharmacotherapy, patients should also enhance nutrition with a high-protein diet, calcium, and various vitamins. High protein is beneficial for the formation of bone matrix, and calcium supplementation can promote calcium balance. Milk, rich in protein and calcium, is an ideal treatment diet, and it is also advisable to take appropriate amounts of calcium tablets, vitamin D, and vitamin C.

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Written by Shen Li Wen
Obstetrics and Gynecology
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Menopausal osteoporosis manifestations

Women experience osteoporosis during menopause, generally occurring in the later stages of menopause, which is between 9-13 years after menopause. During this period, women may develop osteoporosis. In the early stages, women can experience pain in the lower back, limbs, and joints, which is actually a manifestation of rapid bone loss. Later on, some women may develop a hunched back. Due to the increased brittleness of their bones, they are prone to various fractures, with vertebral fractures being the most common. This is followed by fractures of the distal radius and the neck of the femur.

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Written by Na Hong Wei
Orthopedics
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Osteoporosis detection methods

Osteoporosis is a systemic special disease characterized by low bone mass and damaged bone microarchitecture, which leads to increased bone fragility and susceptibility to fractures. This is the standard set by the World Health Organization in 2017. However, currently in clinical practice, there is no direct method available to measure bone hardness. Therefore, an indirect method is used, which is the measurement of bone density. There are many methods to measure bone density, among which the gold standard is Dual-Energy X-ray Absorptiometry (DXA). Other methods include single photon, single energy X-ray, Quantitative Computed Tomography (QCT), peripheral quantitative CT, and quantitative ultrasound testing.

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Written by Zhao Xin Lan
Endocrinology
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Causes of osteoporosis

Osteoporosis is primarily characterized by a reduction in bone mass, deterioration of bone tissue microstructure, and increased bone fragility, leading to an increased risk of fractures. It is a metabolic bone disease. Some cases are primary, also referred to as postmenopausal osteoporosis, which generally lacks specific causes and is mainly linked to estrogen deficiency. There is also a category known as secondary osteoporosis, which has a variety of causes, primarily secondary to metabolic endocrine disorders such as hyperparathyroidism, Cushing's syndrome, diabetes, and growth hormone deficiency. Additionally, some hematologic disorders, such as leukemia and lymphoma, can lead to osteoporosis. There are also some less common or rare diseases like osteogenesis imperfecta and scurvy that can cause osteoporosis. Furthermore, long-term use of certain medications, such as corticosteroids and anticonvulsants, can lead to osteoporosis. Kidney diseases, such as chronic renal failure and renal tubular acidosis, can also cause osteoporosis.