Does albinism have anything to do with blood type?

Written by Huang Ling Juan
Dermatology
Updated on September 11, 2024
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Albinism is not related to blood type; it is related to genetics. Albinism is a skin and appendage disorder caused by a deficiency or reduced function of tyrosinase. It is somewhat related to hereditary factors, and also to the lack or synthesis obstruction of melanin. If both parents pass the pathogenic gene they carry to their children, then the children may develop this type of albinism. Ocular albinism is usually an X-linked recessive genetic disorder, mainly transmitted from mothers carrying the albinism gene to their sons, leading to the onset of the disease. Albinism is not directly related to blood type. If albinism occurs, it is advisable to consult and treat at a hospital, and to take preventive measures against the disease before pregnancy.

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Written by Zhang Yin Xing
Obstetrics
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How should pregnant women screen for albinism?

Prenatal screening for albinism primarily involves chromosomal testing during pregnancy. Albinism is a single-gene hereditary disease caused by a defect in a single gene. It mainly occurs in children of consanguineous marriages where both parents carry the albinism gene. This is not a routine prenatal screening; it is only conducted if there has been a case of albinism in the family. Fetal chromosomal examination generally takes place between the 16th to 24th weeks of pregnancy during amniocentesis, where fetal cells are collected to conduct genetic testing to determine if the fetus carries the albinism gene.

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Written by Du Rui Xia
Obstetrics
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Can albinism be detected during pregnancy?

Prenatal genetic testing during pregnancy can be used to diagnose albinism. The incidence of albinism is very low, making it a rare disease clinically, yet it is not included in routine prenatal screening programs. If there are family members with albinism, especially couples who have already had children with the condition, prenatal testing and genetic counseling are necessary. Prenatal genetic testing can identify the specific gene mutation sites within the family. Furthermore, it allows for the use of third-generation IVF techniques to select embryos without the paternal or maternal gene mutations, which can then be implanted in the mother's body to prevent the birth of another child with albinism.

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Written by Huang Ling Juan
Dermatology
56sec home-news-image

Does albinism have anything to do with blood type?

Albinism is not related to blood type; it is related to genetics. Albinism is a skin and appendage disorder caused by a deficiency or reduced function of tyrosinase. It is somewhat related to hereditary factors, and also to the lack or synthesis obstruction of melanin. If both parents pass the pathogenic gene they carry to their children, then the children may develop this type of albinism. Ocular albinism is usually an X-linked recessive genetic disorder, mainly transmitted from mothers carrying the albinism gene to their sons, leading to the onset of the disease. Albinism is not directly related to blood type. If albinism occurs, it is advisable to consult and treat at a hospital, and to take preventive measures against the disease before pregnancy.

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Written by Zhang Jian Bo
Dermatology
48sec home-news-image

Vitiligo is what kind of disease?

Albinism is a congenital hereditary skin disease, which primarily manifests as the pigment loss or localized, or complete depigmentation of the skin, hair, and eyes. Clinically, it can be categorized into localized albinism and generalized albinism. The onset of the disease may be significantly related to defects in certain genes, hence it has a strong genetic component. Its manifestation includes whitening of the skin and hair, as well as loss of pigment in the eyes. Due to the lack of pigment, symptoms may include photophobia, tearing, and a decrease in vision. Currently, there are no particularly effective treatments for albinism. The main approach includes avoiding light exposure and applying sunblocks and ointments to prevent the occurrence of skin tumors.

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Written by Huang Ling Juan
Dermatology
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Does albinism have symptoms other than being white?

In addition to light skin, albinism also presents other symptoms. Individuals with albinism usually have white or yellow-white hair that is fine and soft. Their pupils appear red due to the lack of pigment in the choroid, and some might have congenital small pupils. The sclera may be transparent or appear pale red. People with albinism typically experience photophobia, tearing, frequent blinking, nystagmus (eye tremors), and astigmatism. Although most patients are healthy in other body parts, some with albinism may suffer from poor development, short stature, and intellectual disabilities. When albinism affects the eyes, it is accompanied by skin depigmentation, photophobia, and tearing. Excessive exposure to ultraviolet rays can lead to conditions like solar dermatitis, actinic cheilitis (inflammation of the lips), increased wrinkling of the skin, and dilation of capillaries.