Is allergic purpura serious?

Written by Li Jing
Rheumatology
Updated on September 05, 2024
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Firstly, allergic purpura is caused by infections, drugs, or food allergies leading to skin ecchymosis and petechiae; in addition, it can also manifest as joint pain, hematuria, and melena. The presence of protein in a routine urine test along with hematuria or melena often indicates gastrointestinal allergic purpura and renal allergic purpura. The presence of proteinuria suggests kidney involvement, which is the most severe type among various forms of allergic purpura. If it is solely a cutaneous type, no special treatment is needed other than drinking more water and ensuring bed rest to alleviate skin ecchymosis. If proteinuria or hematuria occurs, one must rest in bed until the protein levels improve before resuming activities. Concurrently, corticosteroids and anti-allergy medications should be administered. (Medication should be used under the guidance of a professional doctor.)

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Written by Pan Wu Shan
Nephrology
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Is allergic purpura nephritis easy to treat?

Allergic purpura nephritis is essentially a kidney complication caused by allergic purpura. The main symptoms are that the patient first presents with scattered purple spots on the lower limbs, known as allergic purpura. Subsequently, routine urine tests reveal hematuria or proteinuria, allowing for a diagnosis of allergic purpura nephritis. It cannot be completely cured. Currently, treatment first requires complete quantification of urine protein and a renal biopsy to confirm whether it is allergic purpura nephritis and its severity. Generally, it involves the use of steroids. Typical treatment involves firstly avoiding allergens, so any substances that cause allergies should not be contacted to prevent triggering allergic purpura, and thus prevent the recurrence of purpura nephritis. Additionally, it involves adhering to a low-salt, low-fat diet, and avoiding catching colds or staying up late.

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Written by Liu Li Ning
Rheumatology
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Is allergic purpura contagious?

Allergic purpura is not a contagious disease; it is an autoimmune disorder, and therefore it is not transmissible. This condition is a self-limiting disease commonly found in adolescents and children. It mainly comes in four types: simple, renal, abdominal, and articular. Common symptoms include purpura on the limbs and body, and it may also involve abdominal pain, joint pain, and hematuria among other organ impairments. During the acute phase, bed rest is required. Sometimes, when the kidneys are affected, corticosteroids are necessary for timely treatment. If there is joint swelling and pain, nonsteroidal anti-inflammatory drugs can be used to alleviate pain, and antispasmodic analgesics can be used for abdominal pain.

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Written by Li Jing
Rheumatology
1min 19sec home-news-image

Can allergic purpura be inherited?

Allergic purpura is mostly caused by exposure to infections, medications, or foods, leading to skin and mucous membrane ecchymoses, which are essentially petechiae and a manifestation of vasculitis. It falls under autoimmune diseases, not genetic diseases, and thus is not contagious. Bacterial, viral, mycoplasmal, or parasitic infections are the most common causes. Secondarily, medications and foods can also trigger allergic purpura, such as high-protein foods like seafood and milk. Therefore, if there are symptoms like ecchymoses on the lower extremities accompanied by joint pain, or signs of blood in the stool or black stool, it is necessary to complete routine blood tests, erythrocyte sedimentation rate, and autoimmune antibody tests to rule out other autoimmune diseases. During the acute phase, it is advisable to rest in bed, eat a light diet, avoid infection, and use corticosteroids for anti-allergy treatment if necessary.

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Written by Yang Ya Meng
Rheumatology
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Mild symptoms of allergic purpura

Allergic purpura mainly includes three pathological types. The symptoms of the mild type mainly involve changes in the skin, primarily purpura-like rashes around the lower legs and ankle joints. If there are only skin lesions, it is considered a very mild case of allergic purpura. Additionally, more severe cases may involve kidney impairment, such as the presence of protein in the urine. Some patients primarily experience joint pain, also known as the arthritic type. Another group of patients presents mainly with sudden abdominal pain, primarily known as the abdominal type. Therefore, mild symptoms of allergic purpura might just be typical rashes. As long as there is no involvement of the visceral system, it is considered relatively mild.

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Written by Li Jing
Rheumatology
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Can allergic purpura be cured?

Allergic purpura is a common vasculitic hypersensitivity response, which means that it is a vascular inflammatory response caused by allergies and is particularly prevalent among adolescents, with a higher occurrence in males. Most cases are associated with infections or allergies, with the most common infections being bacterial, viral, parasitic, and mycoplasmal. Seafood and high protein can lead to allergies, triggering allergic purpura. This condition cannot be cured and tends to recur, but as individuals age and their immune system strengthens, the frequency and likelihood of episodes significantly decrease. However, if kidney damage occurs, which means the development of allergic purpura nephritis, it is crucial to regularly monitor kidney function and urine routine to check for the presence of proteinuria. If necessary, cardiac puncture should be performed, and corticosteroids should be administered.