How to treat allergic purpura nephritis?

Written by Li Liu Sheng
Nephrology
Updated on August 31, 2024
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Kidney damage caused by allergic purpura is called allergic purpura nephritis. The main clinical manifestations include joint pain, rash, black stools, abdominal pain, as well as hematuria, increased urinary protein, elevated blood pressure, and even edema and renal insufficiency. During the acute phase of allergic purpura nephritis, patients should rest in bed, and if there is edema, intake of water and salt should be strictly restricted. It is also important to actively identify the allergens to conduct etiological treatment. Intake of certain suspected foods or medications should be prohibited. If the patient has obvious rashes and joint pain, antiallergic medications can be used for treatment. If the effect is not satisfactory, hormones and immunosuppressive agents can be introduced. Depending on the patient's condition, Traditional Chinese Medicine can also be used to invigorate blood circulation and remove blood stasis. If the condition is severe, combined treatment can be considered for better results.

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Written by Yang Ya Meng
Rheumatology
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What should I do if allergic purpura causes vomiting?

Patients with allergic purpura who experience symptoms of vomiting need to be highly vigilant to determine if it is the gastrointestinal type of allergic purpura. In addition to observing the vomiting, we also need to check for symptoms such as abdominal pain and diarrhea in the patient. Regarding treatment, we need to consider the use of corticosteroids. If the patient’s condition allows, immunosuppressants might also be needed. Dietary considerations are also very important; first, it is essential to maintain a light, liquid diet, avoid spicy or tough foods to manage the vomiting symptoms associated with allergic purpura. (The use of medications should be under the guidance of a professional doctor.)

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Written by Li Jing
Rheumatology
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Allergic purpura belongs to which department?

Allergic purpura is a common vasculitis related to hypersensitivity, essentially a type of vasculitis that belongs to hematological diseases. It is mostly caused by infections or allergies to food and drugs, predominantly occurring in adolescents. It is more common in males, but a minority of adults may also develop allergic purpura. The main types include abdominal, renal, articular, mixed, and cutaneous forms. However, when allergic purpura nephritis occurs, presenting with proteinuria or decreased kidney function, it is necessary to visit a nephrology department. Treatment should aim to control proteinuria, protect kidney function, and reduce damage to kidney functions. Therefore, it is essential to visit a nephrologist at this time. Allergic purpura must be differentiated in treatment; if it is merely a cutaneous or abdominal type, a hematologist can manage it. However, if the kidneys are involved, it requires consultation in a nephrology specialty. (Please use medications under the guidance of a professional physician and do not self-medicate.)

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Written by Li Jing
Rheumatology
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What causes allergic purpura?

Allergic purpura commonly occurs in adolescents and children, characterized by frequent relapses and being intractable. It is primarily seen in youth aged between 5 to 14 years. As they age and their immunity strengthens, the frequency of episodes gradually decreases. The most common causes of allergic purpura include infections such as bacteria, viruses, parasites, mycoplasma infections, and allergies to medications and foods, with food allergies mainly stemming from high-protein foods like fish and shrimp, which can easily trigger allergic reactions. Therefore, once skin purpura or proteinuria appears, it is crucial to rest in bed until the pain and proteinuria dissipate and the purpura eases. During treatment, it is also important to avoid cold exposure and overexertion.

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Written by Li Jing
Rheumatology
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What can people with allergic purpura eat?

Firstly, allergic purpura commonly occurs in adolescents and children, mainly between the ages of 5 to 14, and is frequent during the spring and autumn seasons. The most common causes of allergic purpura are infections, drug and food allergies, with infections being the most prevalent cause, such as bacterial, viral, and parasitic infections. Allergic purpura cannot be cured and often relapses. During the acute phase, it is primarily recommended to rest in bed, and to eat a light diet. It is advisable to consume fresh fruits and vegetables, such as oranges, grapes, grapefruits, and kiwis, which are rich in vitamin C, as well as various green leafy vegetables. These foods, rich in vitamin C, are beneficial for recovery and good for the body. Additionally, foods like seafood and mangoes, as well as previously untried fruits and foods, are not recommended during this phase to avoid triggering allergic reactions or worsening the condition.

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Written by Li Jing
Rheumatology
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What are the symptoms of allergic purpura?

The most common clinical manifestations of allergic purpura are bruises on the limbs, black stool, hematuria, and joint pain. It is mainly divided into articular, abdominal, cutaneous, renal, and mixed types. The presence of protein in the urine indicates kidney involvement, which means the condition is most severe. Allergic purpura generally can be alleviated with standard and active treatment, but recurrent attacks affecting the kidneys can lead to persistent purpuric nephritis and proteinuria that do not resolve.