How to treat allergic purpura nephritis?

Written by Li Liu Sheng
Nephrology
Updated on August 31, 2024
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Kidney damage caused by allergic purpura is called allergic purpura nephritis. The main clinical manifestations include joint pain, rash, black stools, abdominal pain, as well as hematuria, increased urinary protein, elevated blood pressure, and even edema and renal insufficiency. During the acute phase of allergic purpura nephritis, patients should rest in bed, and if there is edema, intake of water and salt should be strictly restricted. It is also important to actively identify the allergens to conduct etiological treatment. Intake of certain suspected foods or medications should be prohibited. If the patient has obvious rashes and joint pain, antiallergic medications can be used for treatment. If the effect is not satisfactory, hormones and immunosuppressive agents can be introduced. Depending on the patient's condition, Traditional Chinese Medicine can also be used to invigorate blood circulation and remove blood stasis. If the condition is severe, combined treatment can be considered for better results.

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Written by Li Jing
Rheumatology
49sec home-news-image

Can allergic purpura cause itching?

Allergic purpura is mainly seen in adolescents and children, with a higher incidence in spring and autumn. The most common cause is infection, followed by medications or food, which can also trigger an episode of allergic purpura. The most common symptoms include purpura on the skin and mucous membranes, abdominal pain, blood in stools, hematuria, or joint pain. The purpura primarily affects the limbs, rarely appears on the trunk, and is symmetrically distributed. At this time, the bleeding spots often have no symptoms, meaning there is no itching of the skin. However, when there is concomitant skin edema or hives, itching can occur.

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Written by Li Jing
Rheumatology
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Is allergic purpura serious?

Firstly, allergic purpura is caused by infections, drugs, or food allergies leading to skin ecchymosis and petechiae; in addition, it can also manifest as joint pain, hematuria, and melena. The presence of protein in a routine urine test along with hematuria or melena often indicates gastrointestinal allergic purpura and renal allergic purpura. The presence of proteinuria suggests kidney involvement, which is the most severe type among various forms of allergic purpura. If it is solely a cutaneous type, no special treatment is needed other than drinking more water and ensuring bed rest to alleviate skin ecchymosis. If proteinuria or hematuria occurs, one must rest in bed until the protein levels improve before resuming activities. Concurrently, corticosteroids and anti-allergy medications should be administered. (Medication should be used under the guidance of a professional doctor.)

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Written by Zhang Peng
General Surgery
1min 12sec home-news-image

Is allergic purpura with abdominal pain easy to treat?

Allergic purpura with abdominal pain, also known as abdominal allergic purpura, involves gastrointestinal symptoms associated with allergic purpura, primarily characterized by episodic severe abdominal pain, usually around the navel or lower abdomen, and may sometimes be accompanied by vomiting. Treatment typically involves bed rest, actively identifying the cause, controlling infections, and supplementing relevant vitamins. It's also important to check for any symptoms of gastrointestinal bleeding. If there are signs of gastrointestinal bleeding, strict dietary management is necessary, blood transfusions may be required when needed, and the healing of the gastrointestinal tract must be monitored. Medications to suppress acid or protect the gastric mucosa could be considered. Generally, the prognosis for allergic purpura is favorable, though very few severe cases may experience gastrointestinal complications such as bleeding, intussusception, or even necrosis. Although the prognosis is generally good, relapse is common. (Please use medications under the guidance of a professional physician and do not self-medicate.)

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Written by Li Jing
Rheumatology
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Can allergic purpura be cured?

Allergic purpura mainly occurs in adolescents and children, often in the spring and autumn seasons, and is typically related to bacterial infections, viral infections, and allergies to medications and foods. The most common clinical symptoms include bruises on both lower limbs, bleeding, black stools, joint pain, and abdominal pain. Upon the appearance of bruises on the lower limbs, it is recommended to complete routine blood tests, erythrocyte sedimentation rate, and autoantibody tests to rule out other autoimmune diseases causing skin bruises. During the acute phase, it is necessary to rest in bed, drink plenty of water, and eat a light diet. If there are only simple skin bruises, these may resolve after rest. However, if joint pain, bloody stools, and black stools occur, formal and active treatment is required, as these symptoms will not resolve on their own. Additionally, the presence of blood or protein in urine suggests kidney involvement, indicating that the condition has worsened.

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Written by Liu Li Ning
Rheumatology
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Is allergic purpura contagious?

Allergic purpura is not a contagious disease; it is an autoimmune disorder, and therefore it is not transmissible. This condition is a self-limiting disease commonly found in adolescents and children. It mainly comes in four types: simple, renal, abdominal, and articular. Common symptoms include purpura on the limbs and body, and it may also involve abdominal pain, joint pain, and hematuria among other organ impairments. During the acute phase, bed rest is required. Sometimes, when the kidneys are affected, corticosteroids are necessary for timely treatment. If there is joint swelling and pain, nonsteroidal anti-inflammatory drugs can be used to alleviate pain, and antispasmodic analgesics can be used for abdominal pain.