Can allergic purpura be inherited?

Written by Li Jing
Rheumatology
Updated on September 23, 2024
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Allergic purpura is mostly caused by exposure to infections, medications, or foods, leading to skin and mucous membrane ecchymoses, which are essentially petechiae and a manifestation of vasculitis. It falls under autoimmune diseases, not genetic diseases, and thus is not contagious. Bacterial, viral, mycoplasmal, or parasitic infections are the most common causes. Secondarily, medications and foods can also trigger allergic purpura, such as high-protein foods like seafood and milk. Therefore, if there are symptoms like ecchymoses on the lower extremities accompanied by joint pain, or signs of blood in the stool or black stool, it is necessary to complete routine blood tests, erythrocyte sedimentation rate, and autoimmune antibody tests to rule out other autoimmune diseases. During the acute phase, it is advisable to rest in bed, eat a light diet, avoid infection, and use corticosteroids for anti-allergy treatment if necessary.

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Written by Li Jing
Rheumatology
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What can people with allergic purpura eat?

Firstly, allergic purpura commonly occurs in adolescents and children, mainly between the ages of 5 to 14, and is frequent during the spring and autumn seasons. The most common causes of allergic purpura are infections, drug and food allergies, with infections being the most prevalent cause, such as bacterial, viral, and parasitic infections. Allergic purpura cannot be cured and often relapses. During the acute phase, it is primarily recommended to rest in bed, and to eat a light diet. It is advisable to consume fresh fruits and vegetables, such as oranges, grapes, grapefruits, and kiwis, which are rich in vitamin C, as well as various green leafy vegetables. These foods, rich in vitamin C, are beneficial for recovery and good for the body. Additionally, foods like seafood and mangoes, as well as previously untried fruits and foods, are not recommended during this phase to avoid triggering allergic reactions or worsening the condition.

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Written by Li Liu Sheng
Nephrology
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Is allergic purpura nephritis contagious?

Kidney damage caused by allergic purpura is called allergic purpuric nephritis. The main mechanism of allergic purpuric nephritis is the deposition of immune complexes in the kidneys, causing hematuria, proteinuria, edema, and hypertension. Severe cases of purpuric nephritis may also lead to renal failure. Additionally, patients with allergic purpuric nephritis exhibit systemic symptoms such as skin purpura, abdominal pain, joint pain, and melena. Allergic purpuric nephritis usually occurs in children, and it is not contagious. Unlike viral hepatitis, tuberculosis, and dysentery, it does not spread through respiratory, digestive, or blood pathways.

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Written by Li Jing
Rheumatology
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What are the symptoms of allergic purpura?

The most common clinical manifestations of allergic purpura are bruises on the limbs, black stool, hematuria, and joint pain. It is mainly divided into articular, abdominal, cutaneous, renal, and mixed types. The presence of protein in the urine indicates kidney involvement, which means the condition is most severe. Allergic purpura generally can be alleviated with standard and active treatment, but recurrent attacks affecting the kidneys can lead to persistent purpuric nephritis and proteinuria that do not resolve.

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Written by Li Jing
Rheumatology
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How to deal with abdominal pain from allergic purpura?

The most common clinical manifestations of allergic purpura are bleeding spots on the lower limbs, hematuria, melena, and joint pain. The presence of melena or bloody stools accompanied by abdominal pain often indicates bleeding from the intestinal mucosa. It is recommended to complete a mesenteric vascular color Doppler ultrasound as soon as possible to identify the bleeding sites. At this time, fasting is absolutely necessary, meaning no food or water should be consumed, as this can exacerbate abdominal pain and bleeding. Fasting should continue until the melena and pain are alleviated. If symptoms continue to worsen, surgery may be necessary to prevent intestinal perforation and the onset of acute peritonitis.

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Written by Li Jing
Rheumatology
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What causes allergic purpura?

Allergic purpura commonly occurs in adolescents and children, characterized by frequent relapses and being intractable. It is primarily seen in youth aged between 5 to 14 years. As they age and their immunity strengthens, the frequency of episodes gradually decreases. The most common causes of allergic purpura include infections such as bacteria, viruses, parasites, mycoplasma infections, and allergies to medications and foods, with food allergies mainly stemming from high-protein foods like fish and shrimp, which can easily trigger allergic reactions. Therefore, once skin purpura or proteinuria appears, it is crucial to rest in bed until the pain and proteinuria dissipate and the purpura eases. During treatment, it is also important to avoid cold exposure and overexertion.