Can allergic purpura be inherited?

Written by Li Jing
Rheumatology
Updated on September 23, 2024
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Allergic purpura is mostly caused by exposure to infections, medications, or foods, leading to skin and mucous membrane ecchymoses, which are essentially petechiae and a manifestation of vasculitis. It falls under autoimmune diseases, not genetic diseases, and thus is not contagious. Bacterial, viral, mycoplasmal, or parasitic infections are the most common causes. Secondarily, medications and foods can also trigger allergic purpura, such as high-protein foods like seafood and milk. Therefore, if there are symptoms like ecchymoses on the lower extremities accompanied by joint pain, or signs of blood in the stool or black stool, it is necessary to complete routine blood tests, erythrocyte sedimentation rate, and autoimmune antibody tests to rule out other autoimmune diseases. During the acute phase, it is advisable to rest in bed, eat a light diet, avoid infection, and use corticosteroids for anti-allergy treatment if necessary.

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Written by Li Jing
Rheumatology
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Are there many children with allergic purpura?

Firstly, allergic purpura is commonly found in adolescents and children, with children being the most commonly affected, particularly between the ages of 8 to 15. It typically occurs during the spring and autumn seasons. The most common clinical manifestations are bleeding spots on the lower limbs, hematuria, black stools, and joint pain, which are the most typical clinical presentations. If there are only bleeding spots on the skin, no special treatment is required at this time; rest in bed is necessary, and these bruises can be absorbed. Once the kidneys are involved, it indicates a relatively severe condition, and at this time, active and standard treatment is necessary, including the need to improve routine urine and kidney function indicators. If protein quantification is relatively high, then glucocorticoids are needed, combined with anti-allergic medication. (Medication should be taken under the guidance of a doctor.)

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Written by Li Jing
Rheumatology
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Is allergic purpura serious?

Firstly, allergic purpura is caused by infections, drugs, or food allergies leading to skin ecchymosis and petechiae; in addition, it can also manifest as joint pain, hematuria, and melena. The presence of protein in a routine urine test along with hematuria or melena often indicates gastrointestinal allergic purpura and renal allergic purpura. The presence of proteinuria suggests kidney involvement, which is the most severe type among various forms of allergic purpura. If it is solely a cutaneous type, no special treatment is needed other than drinking more water and ensuring bed rest to alleviate skin ecchymosis. If proteinuria or hematuria occurs, one must rest in bed until the protein levels improve before resuming activities. Concurrently, corticosteroids and anti-allergy medications should be administered. (Medication should be used under the guidance of a professional doctor.)

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Written by Li Jing
Rheumatology
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Can allergic purpura cause itching?

Allergic purpura is mainly seen in adolescents and children, with a higher incidence in spring and autumn. The most common cause is infection, followed by medications or food, which can also trigger an episode of allergic purpura. The most common symptoms include purpura on the skin and mucous membranes, abdominal pain, blood in stools, hematuria, or joint pain. The purpura primarily affects the limbs, rarely appears on the trunk, and is symmetrically distributed. At this time, the bleeding spots often have no symptoms, meaning there is no itching of the skin. However, when there is concomitant skin edema or hives, itching can occur.

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Written by Li Liu Sheng
Nephrology
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How to treat allergic purpura nephritis?

Kidney damage caused by allergic purpura is called allergic purpura nephritis. The main clinical manifestations include joint pain, rash, black stools, abdominal pain, as well as hematuria, increased urinary protein, elevated blood pressure, and even edema and renal insufficiency. During the acute phase of allergic purpura nephritis, patients should rest in bed, and if there is edema, intake of water and salt should be strictly restricted. It is also important to actively identify the allergens to conduct etiological treatment. Intake of certain suspected foods or medications should be prohibited. If the patient has obvious rashes and joint pain, antiallergic medications can be used for treatment. If the effect is not satisfactory, hormones and immunosuppressive agents can be introduced. Depending on the patient's condition, Traditional Chinese Medicine can also be used to invigorate blood circulation and remove blood stasis. If the condition is severe, combined treatment can be considered for better results.

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Written by Zhang Peng
General Surgery
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Is allergic purpura with abdominal pain easy to treat?

Allergic purpura with abdominal pain, also known as abdominal allergic purpura, involves gastrointestinal symptoms associated with allergic purpura, primarily characterized by episodic severe abdominal pain, usually around the navel or lower abdomen, and may sometimes be accompanied by vomiting. Treatment typically involves bed rest, actively identifying the cause, controlling infections, and supplementing relevant vitamins. It's also important to check for any symptoms of gastrointestinal bleeding. If there are signs of gastrointestinal bleeding, strict dietary management is necessary, blood transfusions may be required when needed, and the healing of the gastrointestinal tract must be monitored. Medications to suppress acid or protect the gastric mucosa could be considered. Generally, the prognosis for allergic purpura is favorable, though very few severe cases may experience gastrointestinal complications such as bleeding, intussusception, or even necrosis. Although the prognosis is generally good, relapse is common. (Please use medications under the guidance of a professional physician and do not self-medicate.)