Can acute pancreatitis turn into pancreatic cancer?

Written by He Zong Quan
General Surgery
Updated on January 01, 2025
00:00
00:00

Acute pancreatitis and pancreatic cancer are two diseases that occur in the same organ, the pancreas. However, acute pancreatitis is entirely an inflammatory change, often caused by gallstones, alcohol consumption, binge eating, and hyperlipidemia, with some cases being idiopathic. Pancreatic cancer, on the other hand, is a tumorous lesion and is a malignant tumor that generally requires surgery. Many pancreatic cancer patients are already in the advanced stages when discovered, making the surgery difficult to perform. The prognosis for patients is also completely different. After the onset of acute pancreatitis and treatment, the pancreas recovers, the inflammation subsides, and it does not affect a person's lifespan. However, if pancreatic cancer is clearly diagnosed, the lifespan oftentimes does not extend beyond a few years.

Other Voices

doctor image
home-news-image
Written by Zhou Chen
Oncology
55sec home-news-image

Pancreatic cancer is a type of cancer that arises from the pancreas.

The causes of pancreatic cancer are not yet entirely clear, but its occurrence is associated with smoking, drinking alcohol, high-fat and high-protein diets, excessive consumption of coffee, environmental pollution, and genetic factors. Recent surveys have found that the incidence of pancreatic cancer is significantly higher among diabetics than in the general population. There is also evidence suggesting a certain relationship between chronic pancreatitis and the development of pancreatic cancer, with a notably increased risk of pancreatic cancer among patients with chronic pancreatitis. Additionally, many other factors such as occupation, environment, and geography are somewhat related to the occurrence of this disease. Pancreatic cancer is not a cancer that comes from anger or emotional causes.

doctor image
home-news-image
Written by Liu Liang
Oncology
1min 3sec home-news-image

What does pancreatic cancer ascites mean?

When pancreatic cancer causes ascites, particularly a large amount, we can collect the ascites to search for cancer cells. This generally indicates peritoneal metastasis, or metastasis above the liver which can also cause substantial ascites. In such cases, it typically signifies that the disease has progressed to a late stage, classified as stage IV. Patients in this category are unable to undergo surgery and their treatment primarily involves chemotherapy. If the patient's overall condition is good, chemotherapy can be chosen. If the patient's condition is relatively poor, targeted therapy or oral anti-angiogenesis medications may be selected to control the pancreatic cancer and manage the tumor. If the patient's condition is particularly poor, the approach involves placing a peritoneal drainage tube to remove the ascites and providing the best possible symptomatic supportive care.

doctor image
home-news-image
Written by Zhou Chen
Oncology
1min 10sec home-news-image

What are the symptoms of pancreatic cancer?

The clinical manifestations of pancreatic cancer mainly depend on the location of the cancer, the stage of the disease, whether there is metastasis, and the involvement of adjacent organs. The clinical characteristics include a short disease course, rapid progression, and swift deterioration. The most common symptom is upper abdominal distension and discomfort, pain, though not all patients experience tenderness; if tenderness is present, it aligns with the area of pain felt. Pain is a primary symptom of pancreatic cancer, present whether the cancer is located in the head or the body/tail of the pancreas. Jaundice is a main symptom of cancer in the head of the pancreas, and patients often exhibit more severe gastrointestinal symptoms, most commonly loss of appetite, followed by nausea and vomiting. There might also be diarrhea or constipation, even melena. Diarrhea is often steatorrhea. In the early stages of pancreatic cancer, common symptoms include weight loss and fatigue.

doctor image
home-news-image
Written by Liu Liang
Oncology
56sec home-news-image

How to screen for pancreatic cancer

Pancreatic cancer is a common malignant tumor of the digestive tract. Due to its high malignancy and rapid progression, it severely affects human health. So how should pancreatic cancer patients be screened? Generally, abdominal ultrasound examination is the primary screening method. Another method is the examination of tumor markers, mainly carcinoembryonic antigen (CEA) and CA19-9. CA19-9 is a tumor marker with relatively high specificity and sensitivity for the diagnosis of pancreatic cancer. Therefore, during physical examinations, we can draw blood to check these tumor markers. If there is a significant increase in CA19-9 or CEA, further examinations of the pancreas, such as ultrasound or CT of the pancreas, should be conducted to further investigate whether there is a tumor in the pancreas.

doctor image
home-news-image
Written by Yan Chun
Oncology
50sec home-news-image

What are some symptoms of early pancreatic cancer?

Patients with early-stage pancreatic cancer generally do not exhibit many symptoms, as the tumors are relatively small. Clinically, many patients may experience intermittent mild abdominal pain that does not affect their daily lives. A small number of early-stage patients may exhibit symptoms of general fatigue, mild loss of appetite, nausea, mild acid reflux, or other symptoms of indigestion. Additionally, a few patients in the early stages may experience intermittent episodes of diarrhea. Because these symptoms are not distinctive, patients rarely seek medical attention early. When symptoms like significant epigastric pain and jaundice become apparent, it often indicates that the pancreatic cancer has progressed to a more advanced stage.