Firstly, we need to ascertain the cause of the vomiting and can provide gastric protection and antiemetic treatment accordingly. If the vomiting is due to biliary obstruction caused by pancreatic cancer, resulting in severe jaundice and intense vomiting, in such cases, we can also place a stent surgically to drain the bile. The jaundice might be relieved afterwards, and accordingly, the vomiting symptoms might also be alleviated. Another aspect is, if the vomiting is caused by the tumor itself due to pancreatic cancer, we need to employ chemotherapy or some targeted or antiangiogenic treatments to control the tumor itself, and only then might the symptoms of vomiting be relieved.