How is pancreatic cancer diagnosed?

Written by Liu Liang
Oncology
Updated on September 15, 2024
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The most common symptoms of pancreatic cancer are pain in the upper abdomen and jaundice. During physical examination, a mass in the upper abdomen can be felt, which is a common symptom. When these symptoms appear, further abdominal ultrasound or CT scans should be performed, as these two are the most commonly used imaging methods for diagnosing pancreatic cancer. Additionally, pancreatic MRI or PET-CT can also help enhance the diagnostic accuracy for pancreatic cancer. MRCP and ERCP are also used to assess the bile ducts and to evaluate the feasibility of surgery. Blood tests for pancreatic cancer-related tumor markers, such as carcinoembryonic antigen (CEA) and CA19-9, are commonly performed, with CA19-9 being particularly sensitive and specific for the diagnosis of pancreatic cancer.

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Written by Liu Liang
Oncology
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What is used for pain relief in pancreatic cancer?

If a pancreatic cancer patient is experiencing pain, the choice of pain medication can be based on the specific severity of the pain. For mild pain, mild pain relievers such as ibuprofen sustained-release capsules can be chosen initially. For moderate pain, pain relievers like tramadol can be used. If the daily dosage of tramadol exceeds eight tablets, which is two tablets each time, taken every six hours, and if the pain relief is still inadequate after 24 hours, then it might be appropriate to switch to opioid painkillers such as hydromorphone sustained-release tablets, morphine sustained-release tablets, or morphine.

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Oncology
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Dietary Taboos for Patients with Pancreatic Cancer

Regarding the dietary restrictions for pancreatic cancer patients, there are no specific prohibitions. The main recommendation is to avoid what we typically refer to as junk food, such as barbecued foods and pickled products. Aside from avoiding these foods, it is important to focus on a nutritious and balanced diet, with a good mix of both meat and vegetables. Additionally, because pancreatic cancer patients may experience symptoms like abdominal pain, nausea, vomiting, and a feeling of fullness or discomfort in the upper abdomen, the diet should primarily consist of light and easily digestible foods. In doing so, while ensuring that the patient receives sufficient nutrition, it is best to consume foods that are easy to digest and nutritionally balanced.

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Written by Liu Liang
Oncology
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Late-stage symptoms of pancreatic cancer

Late symptoms of pancreatic cancer include abdominal pain, or sore and swollen back pain, as well as nausea, vomiting, decreased appetite, indigestion, and discomfort of upper abdominal fullness. These are some symptoms affecting the digestive tract. Additionally, there is jaundice caused by tumor compression of the bile duct, as well as skin itching, and even fever. Some patients show clinical manifestations such as ascites when there is metastasis to the liver, or abdominal or retroperitoneal lymph nodes.

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Written by Liu Liang
Oncology
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What should be done if pancreatic cancer has not metastasized?

If pancreatic cancer has not metastasized, then it might be in an early stage. In this situation, consultation with a hepatobiliary surgeon is necessary for the surgeon to assess whether curative surgery can be performed. If the surgeon determines that curative surgery is feasible, this should be the preferred treatment method. Post-operatively, based on whether there are symptoms of recurrence or metastasis, such as vascular tumor thrombi or lymph node metastases, decisions concerning the necessity for adjuvant radiotherapy or chemotherapy should be made based on these high-risk factors for recurrence and metastasis.

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Written by Zhou Chen
Oncology
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How is pancreatic cancer diagnosed?

Ultrasound, CT, MRI, ERCP (Endoscopic Retrograde Cholangiopancreatography), PTCD (Percutaneous Transhepatic Cholangio Drainage), angiography, laparoscopy, tumor markers measurement, cancer gene analysis, etc., are significantly helpful in confirming the diagnosis of pancreatic cancer and determining whether it is resectable surgically. Generally, ultrasound, CA199, and CEA can be used as screening tests. Once pancreatic cancer is suspected, a CT scan is necessary. If the patient has jaundice, especially severe, and a CT scan cannot confirm the diagnosis, ERCP and PTCD can be considered. If internal drainage is successful, surgery can be delayed for one to two weeks for patients with severe jaundice. The diagnostic value of MRI for pancreatic cancer is not superior to CT. If pancreatic cancer has been confirmed but it is uncertain whether it can be surgically removed, choosing angiography and laparoscopy is also clinically meaningful.