The main symptoms of duodenal ulcers include upper abdominal bloating, burping, acid reflux, nausea, vomiting, poor appetite, and indigestion. The characteristic of the upper abdominal pain associated with duodenal ulcers is that the pain intensifies when hungry and decreases after eating. In terms of treatment, the main approach includes acid suppression to protect the stomach, promoting gastric motility, and protecting the gastric mucosa, with the treatment course lasting about six weeks. Additionally, a Carbon-14 breath test is necessary to determine the presence of Helicobacter pylori infection, as Helicobacter pylori has been confirmed as the most important cause of peptic ulcers. If the Helicobacter pylori infection is positive, a 14-day treatment targeting Helicobacter pylori is required, using a regimen of a proton pump inhibitor, two antibiotics, and a bismuth agent.