Is duodenal ulcer bleeding a sign of cancerous change?

Written by Wu Hai Wu
Gastroenterology
Updated on October 19, 2024
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Duodenal ulcer bleeding does not indicate cancerous changes. The duodenal area is relatively thin, so once a duodenal ulcer occurs, it is more likely to lead to complications such as ulcer bleeding and perforation. If vomiting blood occurs with a duodenal ulcer, it indicates that the patient with the duodenal ulcer has a bleeding complication. In terms of treatment, it is first necessary to complete an endoscopic examination, which can include endoscopic hemostasis; secondly, proton pump inhibitors should be used to suppress the secretion of stomach acid and increase the pH level in the stomach; additionally, treatments that protect the stomach lining, such as aluminum hydroxide and magnesium carbonate, should be used. (Medication should be taken under the guidance of a physician.)

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Written by Wu Hai Wu
Gastroenterology
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Is a duodenal ulcer stage II severe?

Stage 2 duodenal ulcer is not considered severe as it indicates that the patient is in the healing phase; thus, it is generally not very serious. Typically, patients in stage 2 can be cured with appropriate medical treatment. The main causes of duodenal ulcers include infection by Helicobacter pylori and the use of certain drugs that irritate the gastric mucosa, such as corticosteroids, anti-rheumatic drugs, and nonsteroidal anti-inflammatory drugs. If a patient with a duodenal ulcer is found to have a Helicobacter pylori infection, treatment involves a two-week quadruple therapy containing bismuth to eradicate Helicobacter pylori, while promptly discontinuing any drugs that are irritating to the gastric mucosa.

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Written by Wu Hai Wu
Gastroenterology
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What should I do if a duodenal ulcer causes diarrhea?

Patients with duodenal ulcers who experience diarrhea should undergo a routine stool examination to rule out diarrhea caused by intestinal infections. If there is no obvious organic disease in the intestines, the diarrhea associated with duodenal ulcers may be due to excessive secretion of stomach acid. It is advisable to consider using medications that suppress the secretion of stomach acid, such as proton pump inhibitors like omeprazole or lansoprazole, etc. You can also use aluminum magnesium carbonate, sucralfate, etc., to protect the stomach lining. For patients with abdominal distension, medications like mosapride can be used to promote gastric motility treatment.

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Written by Wu Hai Wu
Gastroenterology
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Is duodenal bulb inflammation an ulcer?

Duodenal bulb inflammation is not an ulcer. It refers to chronic inflammation of the mucosa of the duodenum without erosion, hence it is not a duodenal ulcer. However, if patients with duodenal bulb inflammation do not receive proper treatment and fail to pay attention to their diet, among other factors, it may potentially develop into a duodenal ulcer. Once a duodenal ulcer occurs, it could lead to potential complications such as pyloric obstruction, gastrointestinal bleeding, and perforation of the duodenal bulb, etc. Therefore, it is crucial for patients with duodenal bulb inflammation to seek active treatment.

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Written by Wang Hui Jie
Gastroenterology
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The difference between gastric ulcers and duodenal ulcers.

The differences between gastric ulcers and duodenal ulcers, in terms of symptoms, include that gastric ulcers often manifest as burning pain, or dull pain, distention pain, etc., usually postprandial pain, occasionally with nighttime pain. If it occurs at the pyloric canal, it lacks typical symptoms, with intense pain likely occurring after eating, and poor drug efficacy, prone to vomiting and pyloric obstruction, perforation, and bleeding. Gastric ulcers have a minor possibility of becoming cancerous. Duodenal ulcer pain is mostly located in the upper abdomen, characterized by hunger pain and midnight pain. Abdominal pain generally eases after eating or taking some antacid medications. For ulcers occurring behind the bulb, nighttime pain and a radiating pain in the back are more common. However, the effectiveness of medication is relatively poor, and it is prone to bleeding. Duodenal ulcers are more likely to lead to perforation and pyloric obstruction, but generally do not become cancerous.

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Written by Wang Li Wei
Gastroenterology
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How to examine the duodenum?

For some diseases of the duodenum, such as inflammation, ulcers, polyps, and tumors of the duodenum, the main examination method is gastroscopy. Gastroscopy can clearly and accurately identify the nature and location of the specific lesions. Additionally, by taking biopsies for pathology, it can specifically determine the benign or malignant nature of the disease, which is very helpful for subsequent treatment plans.