The difference between gastric ulcers and duodenal ulcers.

Written by Ren Zheng Xin
Gastroenterology
Updated on September 06, 2024
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Gastric ulcers and duodenal ulcers are collectively known as peptic ulcers, formed under the self-digestion action of gastric acid and pepsin. Gastric ulcers are more common in middle-aged and elderly people, generally occurring at the lesser curvature of the stomach body. The pain of a gastric ulcer typically appears within an hour after eating, also known as postprandial pain, which gradually eases after one to two hours of digestion and absorption; gastric ulcers can easily lead to bleeding and perforation. Duodenal ulcers are more common in young and middle-aged adults, frequently occurring in the duodenal bulb. Typical symptoms include postprandial pain and midnight pain, which can be alleviated by using antacids. The treatment methods for gastric and duodenal ulcers are similar. Additionally, it is important to pay attention to diet in daily life, eat less spicy, greasy, and irritating food, and consume more soft, easily digestible food.

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How to alleviate nausea from duodenal ulcers?

Duodenal ulcer primarily manifests with symptoms such as abdominal pain, bloating, nausea, vomiting, poor appetite, acid reflux, and belching. The characteristic pain associated with this condition typically diminishes after eating and worsens when hungry. A gastroscopy revealing defects in the duodenal mucosa can confirm a diagnosis of duodenal ulcer. Treatment focuses on acid suppression and gastric protection, enhancing gastric motility, and protecting the gastric mucosa. Additionally, a carbon-14 breath test is conducted to check for Helicobacter pylori infection, a bacterium that can cause peptic ulcers. If the test is positive, a 14-day treatment against Helicobacter pylori is required. By adhering to this treatment protocol, symptoms can be effectively resolved.

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Is duodenal bulb inflammation an ulcer?

Duodenal bulb inflammation is not an ulcer. It refers to chronic inflammation of the mucosa of the duodenum without erosion, hence it is not a duodenal ulcer. However, if patients with duodenal bulb inflammation do not receive proper treatment and fail to pay attention to their diet, among other factors, it may potentially develop into a duodenal ulcer. Once a duodenal ulcer occurs, it could lead to potential complications such as pyloric obstruction, gastrointestinal bleeding, and perforation of the duodenal bulb, etc. Therefore, it is crucial for patients with duodenal bulb inflammation to seek active treatment.

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Symptoms and Treatment of Duodenal Ulcer

Duodenal bulb ulcers often manifest as hunger-like pain in the upper abdomen, which relieves after eating, accompanied by nocturnal pain. Symptoms also include acid reflux, heartburn, nausea, etc. If there is bleeding, symptoms may include black stools and vomiting blood. Treatment depends on whether there is a Helicobacter pylori infection. If there is a Helicobacter pylori infection, antibacterial treatment is required, commonly using a triple or quadruple antibiotic therapy for two weeks. If there is no Helicobacter pylori infection, symptomatic treatment is sufficient, generally using proton pump inhibitors and gastroprotective medications such as bismuth agents. Additionally, it is important to develop good dietary and lifestyle habits to prevent recurrence.

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Where does a duodenal ulcer hurt?

Firstly, the common sites for duodenal ulcers are the anterior and posterior walls posterior to the bulb, as well as the area behind the duodenal bulb itself. The pain symptoms typically show a pattern. For example, the pain occurs in recurrent, cyclical episodes related to eating, manifesting as sporadic abdominal pain about 2cm above the right side of the belly button, more pronounced on an empty stomach, and alleviating after meals. Sometimes, there is also pain during the night. If the ulcer is located behind the duodenal bulb, it often causes back pain. The main cause is usually an infection with Helicobacter pylori, and eradication therapy can generally cure the condition.

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Symptoms of duodenal ulcer

What are the symptoms of duodenal ulcers? Generally, the most obvious symptom of a duodenal ulcer is pain on an empty stomach, which often occurs at midnight or early morning, causing one to wake up from sleep in pain. This is a relatively clear symptom. When this symptom occurs, it is best to go to the hospital for a gastroscope examination as soon as possible. After a clear diagnosis, medication should be taken regularly and according to the treatment course for a cure. Generally, taking medications that inhibit gastric acid secretion and protect the intestinal mucosa, and medications for gastric mucosa, can be quite effective. It is also necessary to test for Helicobacter pylori, and if there is a concurrent infection, antibacterial treatment should be carried out.