Duodenal ulcer primarily manifests with symptoms such as abdominal pain, bloating, nausea, vomiting, poor appetite, acid reflux, and belching. The characteristic pain associated with this condition typically diminishes after eating and worsens when hungry. A gastroscopy revealing defects in the duodenal mucosa can confirm a diagnosis of duodenal ulcer. Treatment focuses on acid suppression and gastric protection, enhancing gastric motility, and protecting the gastric mucosa. Additionally, a carbon-14 breath test is conducted to check for Helicobacter pylori infection, a bacterium that can cause peptic ulcers. If the test is positive, a 14-day treatment against Helicobacter pylori is required. By adhering to this treatment protocol, symptoms can be effectively resolved.