How is endometrial cancer diagnosed?

Written by Liu Jian Wei
Obstetrics and Gynecology
Updated on September 12, 2024
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In the clinical setting, when endometrial cancer is suspected, further pathological examination is required. Generally, endometrial tissue can be obtained through fractional curettage or hysteroscopic endometrial biopsy. The acquired endometrium is then subject to a pathological examination, observing the morphology of the endometrial cells under a microscope. If cancer cells are detected, a diagnosis of endometrial cancer can be made. Therefore, the confirmation of endometrial cancer in clinical practice must be based on pathological examination.

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Written by Shen Li Wen
Obstetrics and Gynecology
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Are uterine polyps and endometrial cancer the same?

Endometrial polyps and endometrial cancer are different. First, both can be induced by hormonal imbalances in the body, but endometrial polyps may also involve inflammatory elements, leading to the formation of polyps. Additionally, the age of onset differs; endometrial polyps are more common in women of reproductive age, whereas endometrial cancer typically occurs after the age of 45. Furthermore, their clinical manifestations vary. Women with endometrial polyps mainly experience changes in menstrual cycles and infertility, and generally, endometrial polyps grow slowly. In contrast, women with endometrial cancer mainly experience abdominal pain, heavy vaginal discharge, or bleeding. In advanced stages, women may exhibit signs of cachexia. These two conditions can be differentiated through diagnostic curettage.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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What to do about endometrial cancer pain?

Endometrial cancer, when cancerous tissues invade local nerves, can cause patients to experience pain. This type of pain is recommended to be alleviated by oral painkillers. Pain caused by cancer is an important factor affecting the quality of life of patients in the middle and late stages of the disease; therefore, in clinical practice, analgesic medications can be administered to relieve symptoms in patients with cancer pain. (Please take medications under the guidance of a doctor.)

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Written by Zhang Lu
Obstetrics
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How many times for endometrial cancer chemotherapy?

Post-surgical treatment for endometrial cancer often requires adjunct therapies, commonly including chemotherapy and radiotherapy. The frequency of chemotherapy primarily depends on whether the pathological results of the endometrial cancer reveal high-risk factors. If no high-risk factors are present, regular observation and follow-ups are generally advised. However, if high-risk factors are present, such as lymph node metastasis or local infiltration, this condition requires 4-6 cycles of chemotherapy after surgery, supplemented by radiotherapy. Thus, for endometrial cancer, if high-risk factors exist, chemotherapy is needed for 4-6 cycles; if no high-risk factors are present, chemotherapy is generally unnecessary, and regular follow-ups suffice.

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Written by Tang Mei Xiang
Obstetrics and Gynecology
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How is endometrial cancer diagnosed?

Endometrial cancer often manifests as vaginal bleeding after menopause, and in women who have not experienced menopause, it often presents as menstrual irregularities. The diagnostic methods for endometrial cancer include the following: 1. Fractional curettage is the most important method for diagnosing endometrial cancer. First, scrape the cervical canal, then sequentially scrape the endometrial tissue from each part of the uterine body, label the specimens separately, and send them for pathological examination together. 2. Cytological examination is a method for screening for endometrial cancer. A specially made uterine cavity suction tube or brush is inserted into the uterine cavity to collect secretions for cytological culture. 3. Hysteroscopic examination allows direct observation of the growth of endometrial lesions and can also obtain live tissue for pathological examination. It involves pelvic ultrasound examination to understand the size of the lesion, surrounding infiltration, etc. 5. Other methods, such as lymphangiography, CT, MRI, and serum CA125 testing.

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Written by Zhang Xiu Rong
Obstetrics and Gynecology
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Is a thick endometrium the same as cancer?

Endometrial thickening is not necessarily cancerous. Causes of endometrial thickening generally include irregular hyperplasia or endometrial polyps, both of which can lead to thickening of the endometrium, but this is not necessarily indicative of cancer. Whether it is endometrial cancer is usually determined if patients with endometrial thickening do not show clear improvement after treatment with medication. Typically, a curettage procedure is performed to collect tissue for pathological examination. If the pathology report indicates endometrial cancer or precancerous lesions, then it will be reported. Therefore, endometrial thickening is not necessarily indicative of endometrial cancer, and it can occur with conditions like endometrial polyps or irregular endometrial hyperplasia. Treatment at this stage should be based on the pathological results. Thus, while endometrial thickening should be taken seriously, it is not necessarily cancerous.