Post-surgical treatment for endometrial cancer often requires adjunct therapies, commonly including chemotherapy and radiotherapy. The frequency of chemotherapy primarily depends on whether the pathological results of the endometrial cancer reveal high-risk factors. If no high-risk factors are present, regular observation and follow-ups are generally advised. However, if high-risk factors are present, such as lymph node metastasis or local infiltration, this condition requires 4-6 cycles of chemotherapy after surgery, supplemented by radiotherapy. Thus, for endometrial cancer, if high-risk factors exist, chemotherapy is needed for 4-6 cycles; if no high-risk factors are present, chemotherapy is generally unnecessary, and regular follow-ups suffice.