Is surgery necessary for endometrial cancer?

Written by Shen Li Wen
Obstetrics and Gynecology
Updated on September 15, 2024
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When a woman suffers from endometrial cancer, the primary treatment method is surgery, but there are some special circumstances. For example, if the lesion in the woman is relatively minor, it is atypical hyperplasia, which is a precancerous condition, or it is in the late stage of the disease, or in cases of recurrent endometrial cancer. At this time, treatment can be administered using progestogen drugs, applying high-dose long-term oral intake of effective progestogens, which can suppress the cancerous transformation of the endometrial lining and inhibit the further proliferation of cancer cells. Generally, it involves continuous oral administration for 12 weeks, which is three months, followed by a diagnostic curettage to evaluate the therapeutic effects of the drug. In addition, radiation therapy can also be considered.

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Written by Shen Li Wen
Obstetrics and Gynecology
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Early symptoms of endometrial cancer

When endometrial cancer occurs in women, it first manifests as abnormal proliferation of the endometrium, increased endometrial surface area, and increased secretions, which can increase the pressure inside the uterine cavity, leading to lower abdominal pain in women. Most women can tolerate this pain, but it tends to worsen during vigorous activities or sexual intercourse. Vaginal discharge may become watery and increase. Additionally, some women may experience increased menstrual flow or irregular vaginal bleeding. Over time, this can lead to blood loss anemia in women, manifesting as dizziness, fatigue, and changes in appetite.

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Written by Du Rui Xia
Obstetrics
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Can endometrial cancer patients become pregnant?

After the occurrence of endometrial cancer, it is not possible to become pregnant. This is because, after pregnancy, a woman's immunity decreases, and her resistance to illness declines. This will affect the woman's health and may exacerbate the condition of endometrial cancer. Additionally, women with endometrial cancer, even if they become pregnant, may experience miscarriages as the embryo cannot develop normally, and even many harmful symptoms might occur, affecting the woman's health. Therefore, women with endometrial cancer should take contraceptive measures to prevent unintended pregnancies.

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Written by Yan Chun
Oncology
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What are the symptoms of endometrial cancer?

Patients with endometrial cancer mainly experience symptoms in three areas: First, obvious symptoms caused by local tumors in the uterus, such as irregular vaginal bleeding, changes in the menstrual cycle, a sense of fullness and dull pain in the lower abdomen and pelvic area, along with significant discomfort and pain. Second, clinical symptoms caused by metastatic lesions. Endometrial cancer can spread through three pathways, which after dissemination can cause a variety of symptoms, such as abdominal pain, bloating, constipation, headache, vomiting, movement disorders, chest tightness, coughing, wheezing, and difficulty breathing. Some patients may also experience bone pain. Third, systemic symptoms, which are typically seen in advanced stages of endometrial cancer and commonly include cachexia, fever, and others.

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Written by Li Li Jie
Obstetrics and Gynecology
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Is endometrial tofu dregs-like a sign of endometrial cancer?

Endometrial cancer usually manifests in five main aspects. First, irregular vaginal bleeding, which is typically light but can be moderate in some patients. If the patient is postmenopausal, the bleeding often appears as either continuous or intermittent. Second, menstrual disorders, which are a common symptom of endometrial cancer as it is a malignant tumor occurring in the endometrium and significantly affects menstruation. Third, vaginal discharge, where some patients may experience a discharge of thin, white secretions, or a very small amount of bloody discharge in the early stages of the disease. Fourth, pain; once a patient develops endometrial cancer, the tumor may cause bleeding and possibly lead to infection. Fifth, abdominal masses, which can occur if there is a combination of large uterine fibroids or in advanced stages, potentially leading to the formation of large masses in the pelvic cavity due to the spread of a uterine cavity abscess.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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How is endometrial cancer diagnosed?

In the clinical setting, when endometrial cancer is suspected, further pathological examination is required. Generally, endometrial tissue can be obtained through fractional curettage or hysteroscopic endometrial biopsy. The acquired endometrium is then subject to a pathological examination, observing the morphology of the endometrial cells under a microscope. If cancer cells are detected, a diagnosis of endometrial cancer can be made. Therefore, the confirmation of endometrial cancer in clinical practice must be based on pathological examination.