Does hand, foot and mouth disease hurt?

Written by Yan Xin Liang
Pediatrics
Updated on September 26, 2024
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Hand, foot, and mouth disease is caused by an intestinal virus, mainly manifested in children as blisters on the hands, feet, mouth, and buttocks. Some cases may involve fever, while others may have no fever or only mild, low-grade fever. Oral and pharyngeal blisters are quite common, causing oral pain and discomfort. Many children who contract hand, foot, and mouth disease experience a decrease in appetite, which is related to oral and pharyngeal blisters causing pain that affects swallowing and eating.

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Written by Yao Li Qin
Pediatrics
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Is hand, foot, and mouth disease serious?

Hand, foot, and mouth disease is a contagious viral infection primarily characterized by scattered vesicular or papular rashes on the hands, feet, mouth, and buttocks. It is generally a mild condition, and typical symptoms include fever and rash. It can be treated with oral medications and by taking care of oral and skin hygiene, usually healing quickly. Severe cases caused by the EV71 virus can lead to varying degrees of intracranial pressure. In such serious cases, prompt treatment with mannitol and furosemide to reduce intracranial pressure is necessary; corticosteroids may also be needed if required. For children with severe hypoxia, timely correction of oxygen deficiency is crucial, along with intravenous fluids to maintain stable blood pressure, respiration, heart rate, and microcirculation. (Please consult a professional physician for medication guidance and do not self-medicate.)

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Written by Yao Li Qin
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Initial symptoms of hand, foot, and mouth disease

Hand, foot, and mouth disease is a common pediatric exanthematous disease caused by an enterovirus infection, primarily manifesting on the hands, feet, mouth, and buttocks with scattered vesicular and pustular rashes. The incubation period for hand, foot, and mouth disease generally ranges from three to five days. The initial stage of the illness may include fever and sore mouth, or discomfort in the throat, leading to reluctance in children to eat. Accompanying symptoms might include mild coughing, runny nose, and throat discomfort. During a physical examination, a doctor may observe scattered small vesicles in the mouth mucosa, or shallow ulcers that have already erupted. These are mainly found on the lingual and buccal mucosa, as well as the mucosa on the inner side of the lips and upper palate. Subsequently, rashes appear on the hands and feet, generally starting as maculopapular rashes that slowly turn into vesicular rashes. These rashes are distributed eccentrically and typically resolve on their own within two to three days without scaling, scarring, or pigmentation. The oral vesicles usually heal on their own within a week. Some children with milder cases may only exhibit rashes or vesicular pharyngitis.

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Late-stage symptoms of hand, foot, and mouth disease

Hand, foot, and mouth disease is an acute infectious disease caused by enterovirus infection. Generally, there are more than twenty types of enteroviruses that cause hand, foot, and mouth disease, but the most common are Coxsackie virus A16 and enterovirus 71. The initial symptoms of hand, foot, and mouth disease are blisters in the hands, feet, and mouth; some cases include fever, while others do not. In later stages, the disease may exhibit recurring fevers, and the blisters on the mouth, hands, feet, and buttocks may burst and crust over. After crusting, the blisters gradually heal, but in some cases, the disease can progress to severe cases. For instance, complications such as encephalitis, brainstem encephalitis, myocarditis can occur, and some cases may develop neurogenic pulmonary edema, pulmonary hemorrhage, and circulatory failure, among others. However, such severe cases are generally rare.

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Written by Yan Xin Liang
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How long should hand, foot, and mouth disease be isolated?

Hand, foot, and mouth disease is an infectious disease caused by enterovirus infection. There are more than 20 common types of enteroviruses, with Coxsackievirus A16 and Enterovirus 71 being the most common. The main clinical symptoms include fever, mouth pain, loss of appetite, and small blisters or ulcers on the hands, feet, and mouth. Most affected children can heal on their own in about a week, so ordinary cases can be isolated for about a week until all the rashes have crusted over and disappeared. However, for severe cases, the isolation period should be extended appropriately, possibly lasting 10-14 days, or even longer.

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Is hand, foot, and mouth disease contagious?

Hand, foot, and mouth disease is a contagious disease caused by an infection of enteroviruses. There are more than 20 types of enteroviruses that cause the disease, with Coxsackievirus A16 and Enterovirus 71 being the most common. The main clinical manifestations of this disease include blisters on the hands, feet, mouth, and buttocks. Some patients may experience fever, while others may have no fever or only a mild fever. The disease is contagious and primarily transmitted through contact. For example, it can be spread through saliva, droplets, hand-to-mouth contact, and contact with the secretions from the blisters, among other methods.