Causes of Hand, Foot, and Mouth Disease

Written by Yao Li Qin

Pediatrics

Updated on December 12, 2024

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Hand, foot, and mouth disease is a rash illness characterized by scattered papules and vesicles on the hands, feet, mouth, and buttocks, caused by an enterovirus infection. It is a contagious disease caused by a viral infection, specifically by Coxsackievirus A16 and Enterovirus 71, which are part of the enterovirus group. Other Coxsackie enteroviruses can also cause hand, foot, and mouth disease. Common enterovirus infections can also lead to hand, foot, and mouth disease. This means that children who have had hand, foot, and mouth disease can potentially get it again, and this is important knowledge for everyone to understand.

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Written by Li Jiao Yan

Neonatology

52sec

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Initial symptoms of hand, foot, and mouth disease

Hand, foot, and mouth disease is a contagious disease caused by viral infection, which is common in infants and toddlers, especially those under the age of three. The main symptoms include fever, accompanied by maculopapular rashes or vesicles on the hands, feet, mouth, and buttocks. Some initial symptoms are similar to having a cough, runny nose, headache, mouth pain, or sore throat. Sometimes there may be drooling; consequently, babies might drink less milk, and there can be nausea and vomiting. Additionally, some children may experience nausea and diarrhea along with other gastrointestinal symptoms. Another major sign is the presence of vesicles in the hands, feet, and mouth, or maculopapular rashes on the buttocks.

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Written by Li Jiao Yan

Neonatology

1min 3sec

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Prevention of Hand, Foot, and Mouth Disease

Hand, foot, and mouth disease is a common contagious exanthematous disease in pediatrics, caused by a viral infection with a certain epidemic nature. Its main modes of transmission include respiratory, digestive tracts, and close contact. During the epidemic, usually in the summer and autumn seasons, it is recommended that parents avoid taking children to public places. If a suspected case is found, timely isolation should be carried out, and close contacts should be quarantined for 7-10 days. Additionally, it's important to maintain good personal hygiene, such as washing hands before eating and after using the toilet, and to keep indoor ventilation in the home. If a child has been in contact with an infection or a suspected case of hand, foot, and mouth disease, it is crucial to monitor the child for any discomfort and check their temperature regularly. If the child feels unwell, take them to the hospital for treatment promptly.

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Written by Yan Xin Liang

Pediatrics

40sec

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How long should hand, foot, and mouth disease be isolated?

Hand, foot, and mouth disease is an infectious disease caused by enterovirus infection. There are more than 20 common types of enteroviruses, with Coxsackievirus A16 and Enterovirus 71 being the most common. The main clinical symptoms include fever, mouth pain, loss of appetite, and small blisters or ulcers on the hands, feet, and mouth. Most affected children can heal on their own in about a week, so ordinary cases can be isolated for about a week until all the rashes have crusted over and disappeared. However, for severe cases, the isolation period should be extended appropriately, possibly lasting 10-14 days, or even longer.

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Written by Yao Li Qin

Pediatrics

1min 11sec

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What should I do about hand, foot, and mouth disease?

Hand, foot, and mouth disease is a common exanthematous infectious disease in children caused by enterovirus infections. Most cases are mild to moderate and can be treated at home with oral medication. Doctors generally prescribe antiviral medications, and if the child's temperature exceeds 38.5 degrees Celsius, antipyretic medications are also required. If there is discomfort in the throat, some medications can be sprayed to relieve local discomfort. For severe cases, such as those caused by EV71 virus infection, it is crucial to be vigilant. This type of infection can lead to symptoms involving the nervous system and may rapidly progress to severe conditions. Therefore, if it is confirmed that the hand, foot, and mouth disease is caused by EV71 infection and the child's condition is serious, hospitalization should be promptly sought. Additionally, for children under three years old, it's important to actively vaccinate against hand, foot, and mouth disease to prevent illness caused by EV71 virus infection.

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Written by Yan Xin Liang

Pediatrics

51sec

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How is hand, foot, and mouth disease transmitted?

Hand, foot, and mouth disease is an infectious disease caused by enteroviral infections. There are more than 20 types of enteroviruses that can cause hand, foot, and mouth disease, but the most common are Coxsackievirus A16 and Enterovirus 71. The main clinical symptoms include pain in the mouth, anorexia, low fever, and the appearance of small vesicles or ulcers on the hands, feet, mouth, and other areas. Most children can recover in about a week, but a few may develop serious complications such as myocarditis, pulmonary edema, and aseptic meningitis. The general transmission routes are through the digestive tract, respiratory tract, and close contact, such as through droplets, sharing utensils, and hand-to-mouth contact, etc.