Does ovarian cancer hyperthermic intraperitoneal chemotherapy work?

Written by Liu Liang
Oncology
Updated on November 05, 2024
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Patients with ovarian cancer are prone to peritoneal metastasis, so many patients develop ascites during the discovery of the disease or its progression. A large amount of ascites is a common concurrent symptom in patients with ovarian cancer. For patients with significant ascites like this, hyperthermic intraperitoneal chemotherapy (HIPEC) can be performed, which involves infusing chemotherapy drugs into the abdominal cavity and then combining it with thermotherapy. This treatment generally has a decent effect, especially in controlling the spread of cancer cells in the peritoneum and managing ascites.

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Written by Liu Liang
Oncology
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early symptoms of ovarian cancer

The early symptoms of ovarian cancer in patients are often not very obvious, so they are not easily noticed. The more common symptom is an abdominal mass, meaning you can feel a lump in the abdomen. In its early stages, the abdominal mass is not large and is not easily detectable. Most patients only discover it during gynecological examinations. As the disease progresses, the mass grows larger and the abdomen visibly expands, leading to symptoms like abdominal pain, bloating, or lower abdominal discomfort. Another symptom is ascites, which is a more common sign in patients with advanced ovarian cancer.

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Written by Liu Liang
Oncology
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Ovarian cancer stage IC means

If it is stage Ic ovarian cancer, it refers to the tumor being confined to one or both ovaries, without involvement of other pelvic organs or distant organs such as the liver or lungs. However, it must meet any of the following conditions: the first is the rupture of the capsule with tumor on the surface; the second is the presence of cancer cells in the ascites or peritoneal lavage fluid. Meeting any of these conditions, along with the tumor being limited to one or both ovaries, classifies it as stage Ic.

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Written by Liu Liang
Oncology
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Does ovarian cancer cause abdominal pain every day?

Patients with ovarian cancer often experience abdominal pain as a common symptom. This is because ovarian cancer can widely implant itself within the pelvic and abdominal cavity, or directly invade the uterus, fallopian tubes, and other tissues and organs within the pelvis, resulting in symptoms of abdominal pain. However, not every patient with ovarian cancer will necessarily exhibit abdominal pain as a clinical symptom, nor is it the case that abdominal pain will occur every day. For instance, some patients with early-stage ovarian cancer may have more concealed clinical presentations and may not experience any specific discomfort. They might discover the disease through physical examinations, gynecological exams, or through ultrasound scans of the uterine adnexa conducted during physical check-ups.

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Written by Liu Liang
Oncology
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Early Symptoms of Ovarian Cancer

Patients with ovarian cancer may have relatively hidden clinical symptoms in the early stages, possibly without any specific discomfort, or just mild lower abdominal bloating or pain. Symptoms tend to become more apparent only when the tumor progressively enlarges or when ascites occur, such as increased abdominal bloating and pain. Furthermore, during a physical examination, a solid or cystic-solid mass can be palpated in the pelvic area. Ascites can also lead to clinical symptoms such as nausea and vomiting. In the late stages, partial intestinal obstruction or symptoms related to pelvic compression may appear.

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Written by Wu Xia
Oncology
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Can ovarian cancer be inherited?

Ovarian cancer, like most tumors, has genetic factors involved in its etiology, but it is not a genetic disease. Only five to ten percent of ovarian cancer patients have a genetic background. More than ninety percent of ovarian cancer cases are sporadic, meaning that if a mother has ovarian cancer, it does not directly inherit to her daughter. However, individuals with a family history of ovarian cancer have a significantly higher risk of developing the disease compared to the general population, especially those who carry mutations in the BRCA1 and BRCA2 genes. These gene mutations can be inherited from parents, so individuals carrying these mutations have a significantly higher risk of developing ovarian cancer than the healthy population.