Early Symptoms of Ovarian Cancer

Written by Liu Liang
Oncology
Updated on September 22, 2024
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Patients with ovarian cancer may have relatively hidden clinical symptoms in the early stages, possibly without any specific discomfort, or just mild lower abdominal bloating or pain. Symptoms tend to become more apparent only when the tumor progressively enlarges or when ascites occur, such as increased abdominal bloating and pain. Furthermore, during a physical examination, a solid or cystic-solid mass can be palpated in the pelvic area. Ascites can also lead to clinical symptoms such as nausea and vomiting. In the late stages, partial intestinal obstruction or symptoms related to pelvic compression may appear.

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Written by Liu Liang
Oncology
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How long can one live with ovarian cancer?

The lifespan of ovarian cancer patients depends on several factors including the specific stage of the cancer, the patient's sensitivity and response to treatment, and the overall health of the patient, leading to significant individual variability. The cancer is typically classified into stages from one to four, with stage one being the earliest and stage four being the most advanced. Generally, patients diagnosed at an earlier stage tend to have a better prognosis and a greater chance of survival compared to those with advanced ovarian cancer. Additionally, patients in advanced stages who respond well to treatments like chemotherapy typically have a better prognosis and longer survival times compared to those who are less responsive to such treatments. Hence, it is impossible to generalize as the individual differences are substantial.

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Written by Liu Liang
Oncology
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Ovarian Cancer Screening Methods

The methods for diagnosing ovarian cancer include imaging studies, such as ultrasonography of the adnexa of the uterus, abdominal CT, or MRI, which can detect ovarian tumors. The next step is to perform a blood test for the tumor marker CA125, which is a relatively specific and sensitive marker for epithelial ovarian cancer; in clinical practice, CA125 levels are generally significantly elevated in patients with ovarian cancer. Additionally, many patients with ovarian cancer, especially those in advanced stages, often develop significant ascites. We can perform abdominal paracentesis to drain the fluid and test the ascites for cancer cells. If cancer cells are found in the ascites and imaging studies reveal an ovarian mass, ovarian cancer can be diagnosed. Furthermore, chest CT and other tests are included to comprehensively assess the staging of the patient.

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Written by Liu Liang
Oncology
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Will ovarian cancer recur after complete resection?

After complete removal of ovarian cancer, there is still a possibility of recurrence, especially in patients with high-risk factors. The recurrence rate can be quite high, for example, if there was rupture of the capsule, low differentiation of the pathology, presence of tumor tissue on the surface of the ovary, severe adhesion of the tumor to the surrounding areas, cancer cells found in the abdominal lavage fluid, or presence of vascular tumor thrombus and nerve invasion. Even after total removal, recurrence can still occur.

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Written by Gong Chun
Oncology
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Early treatment methods for ovarian cancer

The treatment methods for early-stage ovarian cancer should first and foremost include a clear diagnosis and staging. If the staging indicates an early stage, then surgical treatment can be applied. There are many surgical options available, such as cytoreductive surgery, interval debulking surgery, second-look laparotomy, and direct tumor cell reduction surgery. After the surgery, adjuvant chemotherapy can be administered for treatment.

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Written by Gong Chun
Oncology
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How is ovarian cancer treated?

Our treatment principle is that once an ovarian tumor is detected, surgical treatment should be performed. First and foremost, we need to confirm the diagnosis. Second, we should clarify the pathological staging of the ovarian cancer to guide the treatment. It's not a single approach; it's a comprehensive treatment plan. For example, if it is early stage and there are no surgical contraindications, we can proceed with surgical treatment. After the surgery, we can provide adjunctive chemotherapy. If surgery is not immediately feasible, we can also provide neoadjuvant therapy to reduce the stage before proceeding with ovarian cancer surgery. Moreover, there is now targeted therapy and immunotherapy for ovarian cancer, so it is a comprehensive treatment plan.