What are the characteristic manifestations of kidney cancer?

Written by Zhou Qi
Nephrology
Updated on January 16, 2025
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Kidney cancer is a type of malignant tumor. Patients with this disease may exhibit some clinical symptoms. Some patients experience dull pain in the lumbar and back area due to the large growth of the tumor, which compresses the renal capsule. As the tumor grows, it may rupture and bleed, causing the patient to have visible blood in the urine. This type of hematuria is often painless and consistent throughout; patients may also feel a mass in the abdomen. In the early stages of kidney cancer, many patients do not exhibit clinical manifestations or discomfort. Therefore, patients often only exhibit the aforementioned clinical symptoms in a more severe state, later in the progression of the disease.

Other Voices

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Written by Gong Chun
Oncology
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What are the early symptoms of kidney cancer?

Many cases of kidney cancer often have no obvious symptoms in their early stages and are not discovered until the tumor progresses. After the tumor progresses, symptoms may include hematuria, which can be intermittent, painless, and visible throughout its course. There may also be back pain and a lump in the abdomen, which is evident in about twenty percent of cases. Slim individuals might find it easier to detect such lumps. There are also some extrarenal manifestations including fever, weight loss, accelerated erythrocyte sedimentation rate, anemia, hypertension, polycythemia, hypercalcemia, liver function impairment, etc. These symptoms might appear in the early stages. However, symptoms can vary from person to person.

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Written by Xu Chun Hua
Urology
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How is kidney cancer diagnosed?

Hematuria, pain, and lumps are the main symptoms of kidney cancer. If one or two of these symptoms appear, the possibility of kidney cancer should be considered. About half of the patients are found to have incidental kidney cancers, also known as asymptomatic kidney cancers, during physical examinations through incidental findings on ultrasound or CT scans. Some may show early symptoms of metastasis making the diagnosis quite challenging. The preoperative diagnosis of kidney cancer relies on the results of medical imaging examinations such as ultrasound, X-rays, and CT scans. CT scans have a very high confirmation rate for kidney cancer and are currently the most reliable imaging method for diagnosing kidney cancer.

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Written by Xu Chun Hua
Urology
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kidney cancer immunotherapy drugs

The immunotherapy for kidney cancer often involves the use of interferons or interleukins, and the results are generally satisfactory. The effects of radiotherapy and chemotherapy for kidney cancer are not very certain. Typically, after kidney cancer is diagnosed, radical nephrectomy is performed. During the surgery, adequate exposure is essential. The renal hilum should be ligated first to prevent cancer cells from being squeezed into the bloodstream during surgery. It is also necessary to remove the fascia and fat around the kidney, along with the lymph nodes at the renal hilum. Combining these surgical measures with immunotherapy usually yields very ideal results.

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Written by Wang Jian
Urology
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Will there be metastasis after kidney cancer removal?

Currently, all malignancies tend to metastasize. Renal cancer is a common malignant tumor of the kidney in the urinary system. Generally, patients might not exhibit any symptoms in the early stages. The most common symptoms are usually back pain and hematuria, and some patients are diagnosed due to an abdominal mass. The primary treatment for renal cancer is surgical intervention, which is considered the preferred method and is believed to be potentially curative. For patients with stage I, II, III, and IV renal cancer, the survival rates decrease progressively. Patients with stage I and II renal cancer should have follow-ups every three to six months for three consecutive years after surgery, and then annually. Patients with stage III and IV renal cancer should have follow-ups every three months for two years post-treatment, then monthly in the third year, and annually thereafter. Early detection of metastasis is crucial for timely treatment. Therefore, even after nephrectomy, renal cancer might recur, and regular follow-ups are essential.

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Written by Zhou Qi
Nephrology
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Can kidney cancer patients be contagious?

Kidney cancer is not an infectious disease, so it is not contagious. Kidney cancer actually occurs when carcinogenic changes happen in the epithelial cells of the renal tubules, leading to the formation of masses and blood in the urine within the kidneys, and can even cause kidney failure. Moreover, kidney cancer carries a certain risk of metastasis, potentially causing damage to other organs. This disease is not contagious. The so-called infectiousness of a disease is due to the presence of pathogens that can cause infection. For example, hepatitis B can be transmitted because carriers have the hepatitis B virus in their bodies. Kidney cancer, however, does not involve viruses, bacteria, or fungi, so it is not infectious.