Kidney cancer thrombus

Written by Zou De Bo
Urology
Updated on September 17, 2024
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Tumor thrombus is one of the common complications of tumors, and refers to cancer cells in blood vessels or lymphatic vessels similar to blood clots, i.e., cancer cells clustering together, invading the vessels, and causing abnormalities in blood coagulation function, leading to disorders in blood circulation and abnormal coagulation with clustered cancer cells. Generally, the risk of tumor thrombus formation is very high, and patients with tumor thrombus have much worse treatment outcomes than those without. Renal cancer is also a tumor commonly associated with tumor thrombus. Once a tumor thrombus occurs, it indicates that the surgery might be staged quite late, and thus, its treatment results are also relatively poor.

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Written by Zou De Bo
Urology
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Kidney cancer thrombus

Tumor thrombus is one of the common complications of tumors, and refers to cancer cells in blood vessels or lymphatic vessels similar to blood clots, i.e., cancer cells clustering together, invading the vessels, and causing abnormalities in blood coagulation function, leading to disorders in blood circulation and abnormal coagulation with clustered cancer cells. Generally, the risk of tumor thrombus formation is very high, and patients with tumor thrombus have much worse treatment outcomes than those without. Renal cancer is also a tumor commonly associated with tumor thrombus. Once a tumor thrombus occurs, it indicates that the surgery might be staged quite late, and thus, its treatment results are also relatively poor.

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Written by Li Yuan Wei
Urology
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Clinical manifestations of renal cancer

The clinical manifestations and staging of kidney cancer are related to the most common early-stage kidney cancer, late-stage kidney cancer, or metastatic kidney cancer. Generally, early-stage kidney cancer exhibits few clinical symptoms and is often detected during physical examinations, through ultrasonography of the urinary tract, or kidney ultrasonography, where tumors are the most commonly found. Additionally, later stages of kidney cancer often present as swelling pain in the waist area or occasional hematuria. More serious conditions involve feeling a mass in the upper abdomen upon palpation, which is a clinical manifestation. Nowadays, with heightened awareness for health checks, such conditions are generally discovered through these examinations. When major clinical manifestations like hematuria and abdominal masses occur, it indicates that the kidney tumor has already progressed to the mid or late stages.

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Written by Li Yuan Wei
Urology
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What are the characteristics of hematuria in renal cancer?

What we commonly refer to as kidney cancer actually includes two aspects. One is renal cell carcinoma, and the other is renal pelvis cancer or ureteral cancer. The characteristics of hematuria are different in these two types. Renal cell carcinoma, simply understood, grows inside the kidney and is not connected with urine. Only when the kidney tumor grows large enough to breach the kidney or renal pelvis will the tumor rupture and bleed, causing hematuria. This generally occurs in the middle to late stages of kidney cancer. On the other hand, renal pelvis cancer or ureteral cancer exhibits intermittent hematuria in the early stages without significant symptoms, but as it progresses to the middle and late stages, symptoms like kidney hydronephrosis and hematuria slowly appear. When diagnosing these conditions, any occurrence of hematuria must be investigated to determine the cause. Initial screening can be done using urinary system ultrasound, urinalysis, or routine urine tests. More precise methods include enhanced CT or MRI of the urinary system, which facilitate easier diagnosis.

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Written by Zou De Bo
Urology
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Post-nephrectomy care for renal cancer

Postoperative care measures for kidney cancer primarily include observing the patient's vital signs. After a radical nephrectomy for a large renal tumor, a significant amount of tissue is removed including the kidney, surrounding adrenal fat, and lymph nodes at the renal hilum, which results in larger surgical wounds and potentially more bleeding. Therefore, it is crucial to closely monitor for signs of bleeding and ensure that transfusions and fluid administrations are unobstructed. Secondly, careful observation and management of the wound drainage tubes are required. Thirdly, for radical nephrectomies, once the patient is past the anesthesia phase and the blood pressure is stable, a semi-reclined position can be adopted. Patients who have undergone partial nephrectomy should remain in bed for one to two weeks to prevent further bleeding, and kidney functions should be monitored. Additionally, attention should be paid to symptoms such as breath holding and difficulty in breathing. Postoperative feeding should commence once gastrointestinal function is restored; thereafter, nutrition should be enhanced to boost bodily resistance. Calming medications may be appropriately used to ease pain, facilitating movement, effective coughing, and expectoration.

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Written by Zou De Bo
Urology
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What are the characteristic symptoms of kidney cancer?

Most kidney cancer patients are discovered during health check-ups, and these patients may account for over 50%-60% of all kidney cancer cases. Among those with symptoms, the most common symptoms are lower back pain and blood in urine. A few patients also present with abdominal masses. 10%-40% of patients can exhibit paraneoplastic syndromes, manifested as high blood pressure, anemia, weight loss, cachexia, fever, abnormal liver function, hyperglycemia, increased erythrocyte sedimentation rate, and other changes. Additionally, symptoms such as bone pain, fractures, cough, and coughing blood can occur due to tumor metastasis.