Is kidney cancer prone to metastasis?

Written by Zou De Bo
Urology
Updated on September 26, 2024
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Kidney cancer in its early stages generally does not metastasize. If it does metastasize, it usually follows several paths: one is hematogenous or lymphatic spread, followed by local diffusion, and then the tumor invades surrounding fat or blood vessels, which is local diffusion. It is also important to note that there is a pseudo-capsule around the kidney cancer that prevents the spread of cancer cells. Metastasis is not likely when the tumor is small, but as the tumor size increases or in some special types of tumor cells, metastasis may occur.

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Written by Zou De Bo
Urology
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Kidney cancer thrombus

Tumor thrombus is one of the common complications of tumors, and refers to cancer cells in blood vessels or lymphatic vessels similar to blood clots, i.e., cancer cells clustering together, invading the vessels, and causing abnormalities in blood coagulation function, leading to disorders in blood circulation and abnormal coagulation with clustered cancer cells. Generally, the risk of tumor thrombus formation is very high, and patients with tumor thrombus have much worse treatment outcomes than those without. Renal cancer is also a tumor commonly associated with tumor thrombus. Once a tumor thrombus occurs, it indicates that the surgery might be staged quite late, and thus, its treatment results are also relatively poor.

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Written by Gong Chun
Oncology
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What are the early symptoms of kidney cancer?

Many cases of kidney cancer often have no obvious symptoms in their early stages and are not discovered until the tumor progresses. After the tumor progresses, symptoms may include hematuria, which can be intermittent, painless, and visible throughout its course. There may also be back pain and a lump in the abdomen, which is evident in about twenty percent of cases. Slim individuals might find it easier to detect such lumps. There are also some extrarenal manifestations including fever, weight loss, accelerated erythrocyte sedimentation rate, anemia, hypertension, polycythemia, hypercalcemia, liver function impairment, etc. These symptoms might appear in the early stages. However, symptoms can vary from person to person.

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Written by Zou De Bo
Urology
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Is kidney cancer prone to metastasis?

Kidney cancer in its early stages generally does not metastasize. If it does metastasize, it usually follows several paths: one is hematogenous or lymphatic spread, followed by local diffusion, and then the tumor invades surrounding fat or blood vessels, which is local diffusion. It is also important to note that there is a pseudo-capsule around the kidney cancer that prevents the spread of cancer cells. Metastasis is not likely when the tumor is small, but as the tumor size increases or in some special types of tumor cells, metastasis may occur.

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Written by Xu Chun Hua
Urology
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Survival rate after early removal of kidney cancer

The prognosis of renal cancer is closely related to its clinical staging. If it is in the early stages, surgery is the preferred treatment and the prognosis is very good. Timely surgery followed by subsequent treatments such as immunotherapy, targeted therapy, etc., is recommended. For early-stage renal cancer, the five-year survival rate after surgical removal can exceed 90%, and some patients may live without issues for over 20 years. How long someone lives specifically also depends on the individual's constitution and physical condition.

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Written by Yan Chun
Oncology
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What are the early symptoms of kidney cancer?

Kidney cancer is a common malignant tumor in the urinary system. Many patients with early-stage kidney cancer do not show any symptoms clinically and are incidentally discovered during medical examinations. Many patients in the early stages may also present with painless hematuria, sometimes as gross hematuria and sometimes as microscopic hematuria. Some patients may experience pain in the kidney area due to blood clots formed after hematuria, mainly presenting as intermittent episodes of mild back pain. Additionally, some patients in the early stages might show symptoms of paraneoplastic syndrome, such as hypertension and fever, but these clinical symptoms generally occur at a very low frequency. When patients present with obvious clinical symptoms, it often indicates that the kidney cancer has metastasized, leading to a clinical presentation of mid-to-late stage kidney cancer.