What causes prostate cancer?

Written by Liu Liang

Oncology

Updated on October 31, 2024

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The causes of prostate cancer are not yet very clear. Its occurrence may be related to gonorrhea of the prostate, or viral and chlamydial infections of the prostate, as well as the intensity of sexual activity and the influence of hormones, which may have some connection to the development of prostate cancer. Additionally, a high-fat diet and some occupational factors, such as excessive exposure to chromium, may also be related to the onset of prostate cancer.

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Prostate cancer IV is stage 4.

Prostate cancer stage IV refers to stage four prostate cancer, which is a common type of male reproductive organ tumor, particularly prevalent among elderly men. Stage four prostate cancer means that the tumor is not confined to the prostate and has already shown corresponding distant metastasis. The most common sites of metastasis for prostate cancer are the bones, followed by the lungs, liver, and others. When metastasis of prostate cancer occurs, it is considered to be at a late stage, and the primary treatments include endocrine therapy, chemotherapy, etc., with a poor prognosis.

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Late-stage prostate cancer with bone metastases: how long can one survive?

Bone metastasis is the most common site of metastasis for prostate cancer. If prostate cancer has metastasized to the bones, it means it is not in its early stages but has entered the advanced stages. However, this type of tumor is not like others with a higher degree of malignancy. If it has a good sensitivity to hormone therapy, after our standardized treatment, the survival time can still be quite long.

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Can prostate cancer be cured?

Prostate cancer, whether it can be cured or not, depends on the specific analysis of the patient with prostate cancer. If it is an early-stage patient, meaning there is no metastasis to distant organs, and it is assessed that radical surgery or radical radiotherapy can be performed, then these early-stage prostate cancer patients still have the hope of being cured through these treatment methods. However, for patients with advanced prostate cancer, such as those who are diagnosed with multiple bone metastases at the onset—a very common clinical occurrence, prostate cancer combined with bone metastasis is very common—these advanced-stage prostate cancer patients cannot be cured through treatment. The purpose of treatment is to alleviate the patient's pain and extend the patient's survival, but these advanced-stage patients cannot be cured.

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androgen deprivation therapy for prostate cancer

Androgen deprivation therapy for prostate cancer includes surgical castration, which can quickly and continuously reduce levels to very low levels. The second is medical castration, which involves the use of analogs of luteinizing hormone-releasing hormone. Currently available products include leuprolide, goserelin, and triptorelin. Third, estrogen therapy, with diethylstilbestrol being the most common estrogen treatment. Surgical castration, medical castration, or estrogen therapy offer similar progression-free survival rates in patients with tumor-related outcomes.

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Where can prostate cancer metastasize to?

When prostate cancer invades surrounding tissues and structures, it can cause a variety of clinical symptoms, including urinary irritation, urinary obstruction, urinary incontinence, sciatica, erectile dysfunction, etc., and can compress causing unilateral or bilateral hydronephrosis. In severe cases, when the tumor invades the rectum, it can cause difficulty in defecation or colon obstruction. When the cancer metastasizes to the bones, it can cause bone pain and pathological fractures, and may also spread to the lungs.