Where can prostate cancer metastasize to?

Written by Zhou Zi Hua
Oncology
Updated on September 20, 2024
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When prostate cancer invades surrounding tissues and structures, it can cause a variety of clinical symptoms, including urinary irritation, urinary obstruction, urinary incontinence, sciatica, erectile dysfunction, etc., and can compress causing unilateral or bilateral hydronephrosis. In severe cases, when the tumor invades the rectum, it can cause difficulty in defecation or colon obstruction. When the cancer metastasizes to the bones, it can cause bone pain and pathological fractures, and may also spread to the lungs.

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Written by Zhou Zi Hua
Oncology
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How is prostate cancer detected?

Digital rectal examination combined with PSA testing is currently recognized as the best screening method for the early detection of prostate cancer. Currently, systematic prostate needle biopsy is the most reliable method for diagnosing prostate cancer. In addition, prostate cancer MRI plays an important role in clinical staging. There is also a whole-body nuclear bone marrow scan that can detect the most common metastatic sites of prostate cancer, including bone metastases.

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Written by Liu Liang
Oncology
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Can prostate cancer be cured?

Early-stage prostate cancer patients can achieve a cure through radical surgery or radical radiotherapy and other treatment methods. Therefore, whether prostate cancer can be cured is related to the stage of the patient's condition. Early-stage prostate cancer patients can be cured through radical surgery or radical radiotherapy. If the cancer is diagnosed at a late stage, with extensive pelvic metastasis or multiple bone metastases, treatment for these late-stage prostate cancer patients primarily revolves around endocrine therapy. Most patients respond well to endocrine treatment; however, for these late-stage prostate cancer patients, the treatment aims to alleviate symptoms and extend survival. Through these treatments, a cure is not achievable.

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Written by Zhou Zi Hua
Oncology
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Prostate cancer radiotherapy is conducted in what way?

Indications for radiation therapy for prostate cancer include clinical stages T1 to T4, M0 to M1. M0-stage prostate cancer patients undergo radiation therapy techniques including external beam radiation and brachytherapy. External beam radiation techniques comprise conventional radiation therapy, three-dimensional conformal radiation therapy, and intensity-modulated radiation therapy. Permanent seed implantation is used only for the treatment of early-stage localized prostate cancer with a good prognosis. External radiation therapy is divided into three categories based on therapeutic objectives: curative, adjuvant, and palliative radiation therapy.

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Oncology
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Pathological classification of prostate cancer

The classification of precancerous lesions of prostate cancer is divided into two categories: intraductal carcinoma of the prostate and atypical adenomatous hyperplasia. Among these, the relationship between intraductal carcinoma of the prostate and prostate cancer is the closest. Intraductal carcinoma of the prostate is currently recognized as a precancerous lesion of prostate cancer, while atypical adenomatous hyperplasia has not been proven to be a precancerous lesion of prostate cancer according to current evidence. However, the biological behavior of this atypical adenomatous hyperplasia is not very clear yet, so it should be closely monitored. The histological classification of prostate cancer mainly includes the majority of acinar adenocarcinoma and a small amount of ductal adenocarcinoma, with acinar adenocarcinoma being a highly invasive malignant tumor.

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Written by Zhou Zi Hua
Oncology
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What are the causes of prostate cancer?

At present, there are many factors that cause prostate cancer, but its exact etiology remains unclear. It may be related to genetic factors, gene changes, prostate gonococcal and chlamydial infections, intensity of sexual activity, and the influence of hormones. Additionally, dietary habits, long-term consumption of high-fat foods, and occupational hazards, such as excessive exposure to chromium, may also be related to the development of the disease.