What are the symptoms of bone metastasis from prostate cancer?

Written by Zhou Zi Hua
Oncology
Updated on September 09, 2024
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Bone metastasis is the most common site of metastasis for prostate cancer, with the lumbar vertebrae being the most common site. Eighty percent of bone metastases in prostate cancer are osteoblastic changes. The main symptoms caused by bone metastasis are bone pain, pathological fractures, anemia, and if the spinal cord is compressed, it can cause paralysis of the lower limbs, weakness, incontinence, and other symptoms.

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Written by Zhou Zi Hua
Oncology
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How long can one live after prostate cancer has spread to the bones?

Bone metastasis is the most common site of metastasis for prostate cancer. If a patient with prostate cancer develops bone metastasis, it means that the cancer is no longer in its early stages and has progressed to a more advanced stage. However, unlike other cancers with a higher degree of malignancy, if the tumor is highly sensitive to hormone therapy, with standardized treatment, the patient's survival time can be significantly extended.

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Written by Liu Liang
Oncology
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Is prostate cancer prone to metastasis?

Prostate cancer most commonly metastasizes to bones, with multiple bone metastases frequently observed clinically. In fact, the majority of prostate cancer patients already have multiple bone metastases by the time they are diagnosed. Therefore, bone is the most common distant organ to which prostate cancer spreads. Other distant organ metastases, such as to the lungs and liver, are less common, unless in very advanced stages of the disease. Additionally, prostate cancer commonly invades locally, spreading to nearby pelvic structures and tissues, such as the bladder and rectum, which is a common form of local invasion and spread.

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Written by Liu Liang
Oncology
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Typical symptoms of prostate cancer

Early-stage prostate patients often do not exhibit significant clinical symptoms. However, when the prostate cancer tumor invades the surrounding tissues and structures, it can cause corresponding clinical manifestations such as urinary tract irritation and urinary obstruction. Symptoms include difficulty urinating or frequent urination, painful urination, and even urinary incontinence, perineal pain, and sciatica. Bone metastasis is a common site of metastasis in prostate cancer patients, causing pain in the affected area and even pathological fractures.

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Written by Zhou Zi Hua
Oncology
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Endocrine therapy after radical prostatectomy for prostate cancer

Endocrine therapy after radical prostatectomy for prostate cancer is equivalent to adjuvant endocrine therapy for prostate cancer. Its purpose is to treat residual lesions, positive residual lymph nodes, and microscopic metastatic foci, thereby improving long-term survival rates. Currently, the indications for adjuvant endocrine therapy are based on postoperative pathology-positive results, positive lymph nodes post-surgery, and postoperative pathology confirmation of stage T3 or T4, but with high-risk factors. According to major guidelines, the duration of adjuvant endocrine therapy should be at least eighteen months.

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Written by Liu Liang
Oncology
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Is chemotherapy for prostate cancer painful?

For patients with advanced prostate cancer, endocrine therapy is primarily used. Chemotherapy is generally chosen when endocrine therapy is resistant and ineffective. The side effects of chemotherapy are similar to those of other chemotherapy treatments. The first is the gastrointestinal side effects, such as nausea, vomiting, decreased appetite, or bloating and abdominal pain. The second is bone marrow suppression, which leads to a decrease in white blood cells and platelets. The side effects of chemotherapy vary with each patient's constitution and other factors. In most cases, with the support of medications for stomach protection, anti-nausea, and increasing white blood cells, the majority of patients can generally tolerate the treatment.