Typical symptoms of prostate cancer

Written by Liu Liang
Oncology
Updated on September 12, 2024
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Early-stage prostate patients often do not exhibit significant clinical symptoms. However, when the prostate cancer tumor invades the surrounding tissues and structures, it can cause corresponding clinical manifestations such as urinary tract irritation and urinary obstruction. Symptoms include difficulty urinating or frequent urination, painful urination, and even urinary incontinence, perineal pain, and sciatica. Bone metastasis is a common site of metastasis in prostate cancer patients, causing pain in the affected area and even pathological fractures.

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Written by Zhou Zi Hua
Oncology
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Commonly used drugs for endocrine treatment of prostate cancer

The purpose of endocrine therapy for prostate cancer is to reduce the concentration of androgens in the body, inhibit the synthesis of androgens originating from the adrenal glands, inhibit the conversion of testosterone to dihydrotestosterone, or block the binding of androgens to their receptors, thereby inhibiting or controlling the growth of prostate cancer cells. The medications include a luteinizing hormone-releasing hormone analogue, with representative drugs being leuprorelin, goserelin, and triptorelin. There is also an androgen-blocking drug, including steroidal drugs with representative drugs like cyproterone acetate, and non-steroidal drugs with representative drugs like bicalutamide and flutamide. Additionally, there are estrogens, with the most common being diethylstilbestrol.

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Written by Yan Chun
Oncology
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What are the late-stage symptoms of prostate cancer?

Prostate cancer is a common malignant tumor in the urinary system. The late-stage symptoms of prostate cancer include the following aspects: Many patients experience urinary symptoms such as frequent urination, urgent urination, and painful urination due to tumor obstruction. Additionally, some patients experience slow urination, difficulty urinating, and even severe urinary retention. A few patients may have painless or painful hematuria. Some patients, due to tumor compression or invasion, experience enlargement and pain of the inguinal lymph nodes, as well as swelling of the lower limbs. Some patients develop bone metastases, clinically manifesting as pain, reduced sensation, or paralysis. Some patients with prostate cancer develop pulmonary metastases, leading to clinical respiratory symptoms such as cough, chest tightness, breathlessness, and difficulty breathing.

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Written by Yan Chun
Oncology
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Is vomiting in prostate cancer due to metastasis to the liver?

Patients with prostate cancer may experience vomiting due to the metastasis of the disease to the liver, causing damage to liver function. However, vomiting could also be caused by other reasons, such as the metastasis of prostate cancer to the peritoneum of the abdominal cavity. Clinically, this can lead to cancerous intestinal obstruction, with symptoms commonly including vomiting, abdominal pain, bloating, reduced bowel movements and gas, or cessation of bowel movements and gas. When prostate cancer metastasizes to the brain, the increased intracranial pressure can also cause symptoms such as vomiting, headache, swelling of the optic disc, hemiplegia, and aphasia. Additionally, some prostate cancer patients may experience vomiting due to toxic side effects from treatments such as chemotherapy and targeted therapy.

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Written by Cui Fang Bo
Oncology
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Prostate cancer IV is stage 4.

Prostate cancer stage IV refers to stage four prostate cancer, which is a common type of male reproductive organ tumor, particularly prevalent among elderly men. Stage four prostate cancer means that the tumor is not confined to the prostate and has already shown corresponding distant metastasis. The most common sites of metastasis for prostate cancer are the bones, followed by the lungs, liver, and others. When metastasis of prostate cancer occurs, it is considered to be at a late stage, and the primary treatments include endocrine therapy, chemotherapy, etc., with a poor prognosis.

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Written by Zhou Zi Hua
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What causes prostate cancer?

The current causes of prostate cancer are not completely understood, but a large amount of research indicates that genetic and environmental factors play a significant role. Dietary factors, such as the intake of a large amount of unsaturated fatty acids, vasectomy, smoking, obesity, and alcohol consumption, also increase the risk of developing prostate cancer. Overall, the occurrence and development of prostate cancer are related to various factors, including both internal causes in the patient and the influence of external factors.