Is stage II-III colon cancer considered late stage?

Written by Cui Fang Bo
Oncology
Updated on November 18, 2024
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Patients with stage II and III colon cancer are not yet considered to be in the classic advanced stages. Current oncology believes that colon cancer is categorized as stage IV and considered advanced when distant metastases occur. Common sites of metastasis for colon cancer include the liver, lungs, and bones. Stage II colon cancer patients do not have metastases to the pericolic lymph nodes, which is relatively early; stage III colon cancer patients have metastases to the pericolic lymph nodes, which is later than stage II, but as long as there are no distant metastases, it does not reach the advanced stage IV.

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Written by Cui Fang Bo
Oncology
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Is stage II-III colon cancer considered late stage?

Patients with stage II and III colon cancer are not yet considered to be in the classic advanced stages. Current oncology believes that colon cancer is categorized as stage IV and considered advanced when distant metastases occur. Common sites of metastasis for colon cancer include the liver, lungs, and bones. Stage II colon cancer patients do not have metastases to the pericolic lymph nodes, which is relatively early; stage III colon cancer patients have metastases to the pericolic lymph nodes, which is later than stage II, but as long as there are no distant metastases, it does not reach the advanced stage IV.

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Written by Shen Jiang Chao
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Colorectal Cancer CT Manifestations and Differential Diagnosis

Early-stage colon cancer is difficult to clearly detect on a CT scan. In the moderate to late stages, colon cancer has more typical manifestations on CT, mainly characterized by thickening of the colon wall, irregular narrowing of the intestinal lumen, and stiffness of the intestinal wall. After enhancement, significant enhancement can be observed. The pericolonic fat space may appear blurred, and in the late stages, small lymph nodes can be seen, and even distant metastasis, most commonly to the liver, can be detected. It is necessary to differentiate colon cancer from colonic inflammation. Inflammatory lesions are usually more widespread and have typical clinical features such as fever and abdominal pain. It is also necessary to differentiate from lymphoma, as lymphomas also cause narrowing of the intestinal lumen but the narrowing is not eccentric and the intestinal wall remains soft, generally not leading to obstruction, whereas in late-stage colon cancer, colonic obstruction can be observed.

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Written by Wu Hai Wu
Gastroenterology
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Is dry, pellet-like stool a symptom of colon cancer?

Dry, granular stools are not necessarily symptoms of colon cancer, but patients with colon cancer may also experience dry, granular stools. Therefore, after exhibiting the above symptoms, patients need to promptly complete an electronic colonoscopy to confirm the diagnosis of the disease. For example, if the symptoms are due to colon cancer, aggressive surgical treatment should be taken, followed by comprehensive treatment including radiotherapy and chemotherapy. If the symptoms are due to functional indigestion causing constipation, treatment should involve using medications to regulate the intestinal flora and relieve constipation.

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Written by Cui Fang Bo
Oncology
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What is the likelihood of metastasis for colon cancer with a certain Ki-67 index?

Currently, the Ki67 index in colon cancer cannot be used as a predictive factor for metastasis. Ki67 reflects the proliferation index of the tumor and is related to the malignancy level of the tumor, but it is not possible to judge the risk of subsequent metastasis based on the Ki67 value. The factors that can be used to assess the risk of postoperative metastasis in colon cancer mainly include the depth of local invasion of the colon cancer, whether there is lymph node metastasis, and the presence of certain specific gene mutations. The deeper the invasion, the higher the risk of metastasis. Patients with lymph node metastasis have a higher risk of distant recurrence and metastasis compared to those without detected lymph node metastasis.

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Written by Wu Hai Wu
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What are the symptoms of stool in colon cancer?

The stool of colon cancer generally appears as mucoid or purulent bloody stool, or there is alternation of diarrhea and constipation. The diagnosis of colon cancer mainly relies on electronic colonoscopy, and routine blood tests as well as carcinoembryonic antigen tests are also of certain reference value. Patients with colon cancer often present with symptoms like anemia and weight loss. Therefore, it is crucial for patients with colon cancer to obtain a definitive diagnosis as early as possible. In addition, early surgical treatment should be adopted. After surgery, adjunct treatments such as radiotherapy and chemotherapy should also be administered.