Third-stage syphilis has no symptoms.

Written by Zhu Zhu
Dermatology
Updated on January 01, 2025
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Once tertiary syphilis has developed, it is highly unlikely for there to be no symptoms. Tertiary syphilis is a late stage of the disease, generally involving the skin, mucous membranes, cardiovascular system, and even the motor and nervous systems. If there are no symptoms present, it is generally not possible to be in the tertiary stage of syphilis. Therefore, if tertiary syphilis occurs, it will not be without symptoms.

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Written by Huang Ling Juan
Dermatology
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What are the symptoms of syphilitic disease?

The symptoms of syphilitic disease are diverse, and syphilis is divided into early syphilis and late syphilis. In the early stages of syphilis, during the primary phase, it usually presents as a hard chancre on the genital area, without obvious pain. In secondary syphilis, it manifests as polymorphic roseola, usually appearing as patches of varying sizes on the trunk, covered with scales, with no significant itching. In tertiary or late syphilis, there can be damage to multiple systems including bones and nerves. Once syphilis is diagnosed, it is essential to treat it early. Early treatment generally leads to good outcomes, with most people recovering. If it progresses to late stages, treatment outcomes are relatively poor. The first choice of treatment for syphilis is long-acting penicillin.

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Written by Zhu Zhu
Dermatology
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How long does it take to cure third-stage syphilis?

The healing time for third-stage syphilis varies from person to person. Third-stage syphilis is considered a late stage of the disease, and the situation is very serious for patients who have developed to this stage. Therefore, the duration of illness for most patients is usually very long; it could be several months or even years, which also depends on the patient's level of aggressive treatment and their own immune resistance. Additionally, it is necessary to consider complications of third-stage syphilis. If there are severe complications involving cardiovascular and nervous systems, or joint damage, recovery can be very prolonged and difficult.

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Written by Zhu Zhu
Dermatology
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Is third-stage syphilis contagious?

Third-stage syphilis is infectious, but its contagiousness is relatively weak compared to first-stage and second-stage syphilis. The titers detected in third-stage syphilis are usually lower, so its infectiousness is comparatively minor. However, third-stage syphilis still has the capability to infect others. Therefore, patients with third-stage syphilis must actively seek treatment and refrain from having sexual relations with others, while also enhancing their own immunity.

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Written by Zhu Zhu
Dermatology
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Early symptoms of syphilis

Syphilis is a sexually transmitted disease caused by the bacterium Treponema pallidum, with the disease course within two years referred to as early syphilis. Not all infected individuals display symptoms; asymptomatic syphilis is also known as latent syphilis. Symptomatic early syphilis primarily manifests as either primary or secondary syphilis. The main symptom of primary syphilis is a chancre, typically occurring as a clear-bordered ulcer in the genital area. It is flesh-colored and neither painful nor itchy. Several weeks after the chancre heals, secondary syphilis can develop, characterized by a rash that may resemble other skin conditions. Common manifestations include macules, papular macules, copper-red papules on hands and feet, flat condyloma, and syphilitic alopecia. Individuals who suspect they may have been exposed to syphilis should visit a hospital for a blood test to detect syphilis antibodies. Antibodies can usually be detected four weeks after infection, and a negative result three months later can rule out syphilis.

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Written by Zhu Zhu
Dermatology
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Can third-stage syphilis be cured?

Third-stage syphilis can potentially be fatal, but this is not absolute. With proper and timely treatment, it can gradually improve. Third-stage syphilis is the most severe and latest stage of the disease, also known as late-stage syphilis. This stage often affects our skin, bones, cardiovascular system, and even the nervous system. When these systems are affected, corresponding complications can arise. If left untreated, late-stage complications can lead to death. However, if treated early, there is a possibility of cure over time.