The symptoms of syphilitic disease are diverse, and syphilis is divided into early syphilis and late syphilis. In the early stages of syphilis, during the primary phase, it usually presents as a hard chancre on the genital area, without obvious pain. In secondary syphilis, it manifests as polymorphic roseola, usually appearing as patches of varying sizes on the trunk, covered with scales, with no significant itching. In tertiary or late syphilis, there can be damage to multiple systems including bones and nerves. Once syphilis is diagnosed, it is essential to treat it early. Early treatment generally leads to good outcomes, with most people recovering. If it progresses to late stages, treatment outcomes are relatively poor. The first choice of treatment for syphilis is long-acting penicillin.