Can third-stage syphilis be cured?

Written by Zhu Zhu

Dermatology

Updated on September 22, 2024

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Third-stage syphilis can potentially be fatal, but this is not absolute. With proper and timely treatment, it can gradually improve. Third-stage syphilis is the most severe and latest stage of the disease, also known as late-stage syphilis. This stage often affects our skin, bones, cardiovascular system, and even the nervous system. When these systems are affected, corresponding complications can arise. If left untreated, late-stage complications can lead to death. However, if treated early, there is a possibility of cure over time.

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Written by Luo Hong

Dermatology Department

49sec

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Can syphilis be completely cured?

Syphilis can generally be completely cured nowadays, except neurosyphilis which is somewhat harder to treat, as ordinary syphilis is curable and neurosyphilis may relapse occasionally. However, most current cases of syphilis fall into categories of latent, primary, or secondary syphilis. Tertiary syphilis is less common, and forms such as neurosyphilis and osteal syphilis belong to this stage. Therefore, when treated at a regular hospital with a standard treatment regimen, primarily using penicillin, administered as a long-acting intramuscular injection once a week, the recommended course of treatment usually consists of three to four weeks. If there is an allergy to penicillin, doxycycline can be used as an oral substitute for half a month.

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Written by Zhu Zhu

Dermatology

1min 18sec

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Early symptoms of syphilis

Syphilis is a sexually transmitted disease caused by the bacterium Treponema pallidum, with the disease course within two years referred to as early syphilis. Not all infected individuals display symptoms; asymptomatic syphilis is also known as latent syphilis. Symptomatic early syphilis primarily manifests as either primary or secondary syphilis. The main symptom of primary syphilis is a chancre, typically occurring as a clear-bordered ulcer in the genital area. It is flesh-colored and neither painful nor itchy. Several weeks after the chancre heals, secondary syphilis can develop, characterized by a rash that may resemble other skin conditions. Common manifestations include macules, papular macules, copper-red papules on hands and feet, flat condyloma, and syphilitic alopecia. Individuals who suspect they may have been exposed to syphilis should visit a hospital for a blood test to detect syphilis antibodies. Antibodies can usually be detected four weeks after infection, and a negative result three months later can rule out syphilis.

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Written by Huang Ling Juan

Dermatology

1min 9sec

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What are the symptoms of syphilis in women?

In the early stages of syphilis in women, a hard chancre appears, often accompanied by swollen inguinal lymph nodes. These nodes are about the size of a finger, relatively hard, non-fusing, painless, and without tenderness; their surfaces exhibit no redness, swelling, or signs of inflammation such as fever. The lymph fluid from a puncture will contain Treponema pallidum (the syphilis bacterium). During the early stage of syphilis, the appearance of a hard chancre significantly increases the positivity rate for syphilis. If the hard chancre is not treated timely, it generally disappears naturally within three to four weeks, after which it enters the latent phase of secondary syphilis. The second stage of syphilis is typically characterized by patches of varying-sized erythemas on the trunk and copper-red, symmetrical maculopapular rashes on the palms and soles. Upon detection of syphilis, prompt and thorough treatment is essential.

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Written by He Jing

Obstetrics and Gynecology

1min 5sec

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Is fungal vaginitis related to syphilis?

Yeast vaginitis and syphilis are unrelated. Yeast vaginitis is caused by a disruption in the vaginal environment leading to an infection with Candida albicans, resulting in increased vaginal discharge. This is accompanied by itching of the vulva and the discharge may appear like cottage cheese or have a curd-like texture. However, syphilis is caused by the infection of the bacterium Treponema pallidum. It is a sexually transmitted disease characterized primarily by painless ulcers on the genitals. The treatment methods for the two are also different. Yeast vaginitis can be treated by external washing with baking soda and inserting clotrimazole vaginal suppositories, typically resolving within about a week. Treatment for syphilis, on the other hand, generally involves intravenous injections of penicillin. (Medication use should be supervised by a professional doctor.)

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Written by Zhu Zhu

Dermatology

53sec

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Can third stage syphilis be detected?

Third-stage syphilis can be detected. Syphilis is divided into primary, secondary, and tertiary stages, with the severity progressively increasing from the primary to tertiary stage, making tertiary syphilis a relatively advanced and serious condition. It can be detected by measuring the titers in serum, although the titers in tertiary syphilis may be lower than in the primary and secondary stages, and may sometimes present as negative. However, through the symptoms of tertiary syphilis, particularly some complications affecting the skin, cardiovascular system, bones, joints, and other organs, combined with the titer levels, it can definitely be detected.