What are the symptoms of tertiary syphilis?

Written by Zhu Zhu
Dermatology
Updated on September 21, 2024
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Tertiary syphilis belongs to the latest stage of syphilis. If a patient develops tertiary syphilis, their symptoms are generally very severe, mainly involving the skin, cardiovascular system, musculoskeletal system, and even the nervous system. In particular, when the nervous system is involved, symptoms such as drowsiness and confusion may occur. Cardiovascular involvement can lead to related cardiovascular symptoms, and if the musculoskeletal system is affected, symptoms generally appear in the bones.

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Written by Zhu Zhu
Dermatology
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Will third-stage syphilis be asymptomatic?

In the case of third-stage syphilis, it is generally not asymptomatic, as it is already a late stage of the disease that invades multiple systems, such as the musculoskeletal system, nervous system, and even the cardiovascular system. When these systems are invaded, they become damaged, leading to various complications. Therefore, third-stage syphilis typically presents with various signs of organ dysfunction, and it is unlikely to be without any symptoms once it has progressed to this stage.

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Written by Zhu Zhu
Dermatology
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How long is the latency period for tertiary syphilis?

The latency period of tertiary syphilis is not clearly defined, but it is certain that once tertiary syphilis appears, the duration of illness in patients generally exceeds two to three years, meaning the latency period is at least two to three years long. Of course, some patients may reach five to ten years. This depends on each individual's resistance as well as the virulence and amount of the virus. Additionally, if one contracts tertiary syphilis, it is crucial to seek timely and proper treatment, as it may be life-threatening.

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Written by Fu Ye Song
Hematology
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Can a routine blood test detect syphilis?

Syphilis is a contagious disease, and we cannot detect syphilis through routine blood tests, as these tests only measure elements such as the number of white blood cells, red blood cells, and platelets in the blood. Since syphilis is caused by an infectious agent, it cannot be detected through routine blood tests. It can only be detected by checking for antibodies using methods like ELISA immunofluorescence. Therefore, routine blood tests cannot detect syphilis.

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Written by Li Chang Yue
General Surgery
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Is cervical lymphadenopathy related to syphilis?

Enlargement of cervical lymph nodes is somewhat related to syphilis. Although cervical lymph node enlargement is not necessarily solely caused by syphilis, if syphilis progresses to its secondary or tertiary stages, it tends to cause lymph node enlargement, and severe cases may even lead to ulceration. This happens because after a syphilis infection, immune responses in the lymph cells are triggered by the Treponema pallidum, leading to the enlargement of cervical lymph nodes, and also possibly the lymph nodes under the arms and in the groin area. In such cases, it is advised to seek timely medical attention, complete the necessary immunological testing, and ensure an accurate diagnosis of syphilis. If cervical lymph node enlargement occurs, prolonged treatment with penicillin should be administered, as it effectively controls the Treponema pallidum and can help reduce the severity of the lymph node enlargement.

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Written by Zhu Zhu
Dermatology
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Does tertiary syphilis have titers?

If one is suffering from stage three syphilis, syphilis titers will be present. However, syphilis titers do not always correlate directly with the severity of the condition. It is possible for the titers in stage one and two syphilis to be higher than in stage three. It's often the case that stage three syphilis represents the late stages of the disease, and the titers might decrease as the disease progresses into these later stages. Examples include titers such as 1:8 or 1:4, although some patients might exhibit titers of 1:16.