If one is suffering from stage three syphilis, syphilis titers will be present. However, syphilis titers do not always correlate directly with the severity of the condition. It is possible for the titers in stage one and two syphilis to be higher than in stage three. It's often the case that stage three syphilis represents the late stages of the disease, and the titers might decrease as the disease progresses into these later stages. Examples include titers such as 1:8 or 1:4, although some patients might exhibit titers of 1:16.