Can a tetanus shot be administered again?

Written by Li Chang Yue

General Surgery

Updated on November 17, 2024

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If a tetanus shot is administered within 24 to 48 hours after injury, it can effectively prevent tetanus. However, if the tetanus shot is given a week or more after the injury, the effectiveness and relevance of the booster are generally not ideal. In such cases, tetanus immunoglobulin can be used for comprehensive antibody therapy to treat and prevent tetanus. Therefore, when the body sustains external injuries or certain infectious foci, it is crucial to promptly administer a tetanus shot intramuscularly, ideally within 24 hours, to effectively stimulate the body to produce the corresponding antibodies for protection.

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Written by Li Jin Quan

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Can tetanus be cured?

Tetanus is a curable disease. It is usually caused by an infection with the tetanus bacillus, which produces a specific infection in the human body. Clinically, it is mainly manifested as muscle tension and rigidity, with the primary symptoms being difficulty opening the mouth, a sardonic smile, neck stiffness, and opisthotonos. In severe cases, it can lead to respiratory confusion, respiratory arrest, or cardiac arrest. Therefore, patients with tetanus should go to the hospital for treatment as soon as possible. With standardized and systematic treatment, the vast majority of patients can be cured.

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How is tetanus diagnosed?

For the diagnosis of tetanus, it mainly relies on relevant medical history and clinical manifestations. In terms of laboratory diagnosis, most cases involve culture of Clostridium tetani from wound tissue or polymerase chain reaction testing. Generally, a positive result can confirm a diagnosis of tetanus, but a negative result does not rule it out. Most laboratories are unable to perform these tests, and even if tetanus antibodies reach a protective level, it does not exclude a diagnosis of tetanus. If the patient has a clear history of injury or animal bites, and presents with symptoms such as lockjaw, a sardonic smile, muscle rigidity, difficulty swallowing, or persistent spasms, tetanus should be considered promptly and relevant treatment initiated.

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Written by Xu Jun Hui

General Surgery

52sec

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Does a tetanus shot stimulate the brain?

Tetanus shot, if administering tetanus toxoid, a skin test is required before injection. If the skin test is negative and there is no allergy, then the injection can proceed without stimulating the brain. A small proportion of patients undergoing anti-tetanus treatment might experience some uncomfortable reactions, commonly allergies, fever, and symptoms of vomiting. Generally, these can be alleviated with rest or symptomatic treatment. Only less than 1% of patients may experience seizures or coma, which are very rare reactions. If such reactions occur, it is urgent to go to a formal hospital for symptomatic and supportive treatment. For the vast majority of tetanus shots, if administered in a formal hospital and the patient has a negative skin test, or if given tetanus immunoglobulin, it does not stimulate the brain.

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Written by Xu Jun Hui

General Surgery

43sec

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When to get a tetanus shot?

Tetanus is caused by the invasion of the body by tetanus bacillus, a type of anaerobic bacterium that generally thrives in anoxic environments or heavily contaminated wounds such as those exposed to polluted soil or rust. Therefore, if the wound is deep, is in an anoxic environment, or is severely contaminated with soil, rust, or is an open fracture with expanded area, explosive injury, gunshot wound, or animal bite, tetanus treatment is required. Tetanus injections include tetanus toxoid, which requires a skin test, and tetanus immunoglobulin, which does not require a skin test, with an injection generally recommended within 24 hours.

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Written by Xu Jun Hui

General Surgery

39sec

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How to administer an injection if the tetanus skin test is negative

A negative tetanus skin test indicates that there is no allergy to tetanus antitoxin, and 1500 to 3000 units of tetanus antitoxin can be directly administered via intramuscular injection in the upper arm or buttock. If the wound is heavily contaminated or the injection is not timely, the dose may be doubled or tripled at discretion, and it is also necessary to clean and dress the wound. The purpose of administering tetanus antitoxin via intramuscular injection is to prevent infection by Clostridium tetani. Therefore, patients with heavily contaminated or deep wounds must receive tetanus antitoxin treatment.