Is the pertussis vaccine a live vaccine?

Written by Li Jian Wu
Pulmonology
Updated on January 20, 2025
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The pertussis vaccine is a type of attenuated live vaccine, which clinically is mainly part of a combination vaccine that includes pertussis, diphtheria, and tetanus, commonly referred to as the DTP vaccine. Normally, a baby should receive the first dose at three months of age, followed by the second dose in the fourth and fifth months, as part of basic immunization. Between the age of eighteen months and two years, another dose is administered to boost immunity, which after producing lifelong antibodies, prevents reinfection with the disease.

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Written by Li Jian Wu
Pulmonology
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Pertussis is diagnosed through what?

Whooping cough is a respiratory infectious disease, generally diagnosed through typical clinical symptoms and laboratory test results. Typical symptoms include paroxysmal, spasmodic coughing, which can also lead to flushed face and ears, runny nose, acute sickly appearance, while some patients may have a cough that sounds like a puppy's bark and others may exhibit a crowing sound during inhalation. During this period, sputum pathogen culture or other auxiliary examinations can be used for diagnosis, and sensitive antimicrobial drugs can be chosen for anti-inflammatory treatment.

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Written by Li Jian Wu
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How to Read Pertussis Test Results

The test for whooping cough is to see if there are any pathogens in the body. If it is confirmed that there is Bordetella pertussis, it can be determined that this disease causes spasmodic coughing, which might be prolonged and recurrent. It may also lead to fever, breathing difficulties, cyanosis of the lips, and signs of hypoxia, requiring symptomatic treatment first. At the same time, selecting macrolide antibiotics to kill the Bordetella pertussis, maintaining a good mental attitude, and ensuring that the room temperature and humidity are kept at appropriate levels are important. Attention should also be paid to the disinfection of the air. Additionally, as it is a communicable disease, isolation treatment is recommended to prevent cross-infection. It is important to adjust your mental attitude, follow the course of medication, and have regular check-ups.

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Written by Li Jian Wu
Pulmonology
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whooping cough symptoms

Whooping cough is a common respiratory infectious disease, mainly caused by infection with Bordetella pertussis. Typical symptoms include colds, runny nose, etc., and feature paroxysmal coughing. The main characteristic is paroxysmal, spasmodic coughing that occurs in strings, with more than ten or even dozens of coughs at a time. The coughing increases abdominal pressure, leading to nausea and vomiting. Infants and young children may also experience a barking cough and wheezing. Some may also experience symptoms such as urinary and fecal incontinence, flushed face, runny nose, teary eyes, and cyanosis of the lips. Once diagnosed, it is important to promptly select sensitive antibiotics for anti-inflammatory treatment. Currently, the main approach to managing this disease is prevention, including timely vaccination against whooping cough.

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Written by Li Jian Wu
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What causes fever in pertussis?

Pertussis, a symptom caused by the infection of Corynebacterium diphtheriae or Bordetella pertussis, facilitates the presence of these substantive pathogens in the body. These pathogens stimulate the body's temperature regulation center, leading to immune fever symptoms. This is a reaction where the body's resistance is fighting against these pathogens, causing a rise in body temperature which is considered normal. During the acute phase, symptomatic treatment should be administered. At the same time, based on the type of infectious pathogen, a sensitive antimicrobial agent should be chosen for etiological treatment. Additionally, it's important to drink plenty of fluids and maintain clean indoor air.

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Written by Li Jian Wu
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Whooping cough vaccine at what age?

The pertussis vaccine is generally administered within the first year of age. Under normal circumstances, children should be taken to hospitals or public health prevention stations for vaccination according to the course of treatment. The first dose starts at the third month after birth, followed by the second dose at four months and the third dose at five months old. A booster can be administered when the baby is two years old. The DTP vaccine used in clinics mainly consists of three components: pertussis, diphtheria, and tetanus.