Is the pertussis vaccine a live vaccine?

Written by Li Jian Wu
Pulmonology
Updated on January 20, 2025
00:00
00:00

The pertussis vaccine is a type of attenuated live vaccine, which clinically is mainly part of a combination vaccine that includes pertussis, diphtheria, and tetanus, commonly referred to as the DTP vaccine. Normally, a baby should receive the first dose at three months of age, followed by the second dose in the fourth and fifth months, as part of basic immunization. Between the age of eighteen months and two years, another dose is administered to boost immunity, which after producing lifelong antibodies, prevents reinfection with the disease.

Other Voices

doctor image
home-news-image
Written by Li Ying
Neonatology
1min 18sec home-news-image

After receiving the DTP vaccine, can you still get whooping cough?

The DTP vaccine is a combination of pertussis bacteria, diphtheria toxoid, and tetanus toxoid, which can prevent whooping cough, diphtheria, and tetanus simultaneously. The target group for the DTP vaccine is children aged 3 months to 7 years. The DTP vaccine requires three consecutive shots. Only after the three consecutive injections will sufficient antibodies be produced. However, these antibodies can only be maintained for a certain period of time and do not provide lifelong immunity. Many parents mistakenly think that once their child is vaccinated, they are invulnerable to all diseases, but this is an unscientific notion. The efficacy of vaccines is not 100%. The common basic vaccines currently used generally have an efficacy rate of over 80%, meaning that after vaccination, 80% of people will produce antibodies. However, since the antibody concentration of some vaccines can decrease significantly over time to a level that does not reach the immunity concentration, booster shots are necessary.

doctor image
home-news-image
Written by Li Jian Wu
Pulmonology
54sec home-news-image

Treatment methods for pertussis

For the treatment of whooping cough, the first step should be to drink plenty of water and maintain a suitable indoor temperature and humidity. In terms of medication, it is necessary to choose macrolide antibiotics and adhere to an inflammatory treatment course. Clinically common drugs include erythromycin, roxithromycin, azithromycin, clarithromycin, etc., and generally, medication is required for at least about ten days. At the same time, it is recommended to use antitussive and expectorant drugs. If there are symptoms of breathing difficulty, oxygen inhalation can also be administered. There are many expectorant drugs clinically available, such as carbocisteine or She Dan Chuan Bei liquid, ambroxol oral solution, etc., all of which can serve the function of suppressing coughs and expelling phlegm.

doctor image
home-news-image
Written by Li Jian Wu
Pulmonology
48sec home-news-image

Is whooping cough an infectious disease?

Pertussis, also known as whooping cough, is a contagious disease that is a respiratory tract infection. It primarily spreads through airborne droplets and close daily contact. Clinically, there is a vaccine available for this condition, mainly the DTP (diphtheria, tetanus, and pertussis) vaccine. Following the vaccination schedule and developing antibodies can effectively prevent the disease. This disease has a lengthy course and can easily cause recurrent coughing episodes and persistent symptoms. It is important to correctly understand and be aware of the characteristics of its onset. If suspected, early examination and timely selection of medications for symptom control are essential, along with addressing the underlying cause.

doctor image
home-news-image
Written by Li Jian Wu
Pulmonology
39sec home-news-image

Where to treat whooping cough?

Pertussis, a respiratory infectious disease, is recommended to be checked and treated at local formal medical institutions. Once diagnosed, the main principle is to kill the Corynebacterium diphtheriae and choose sensitive antibiotics, such as macrolide antibiotics like erythromycin, azithromycin, or clarithromycin. Additionally, symptomatic treatment should be provided, including oxygen therapy for breathing difficulties, using medications to relieve bronchial smooth muscle spasms, thinning mucus, and alleviating uncomfortable symptoms such as coughing. It is also important to drink plenty of water, rest, and maintain good hygiene.

doctor image
home-news-image
Written by Li Jian Wu
Pulmonology
43sec home-news-image

Is the pertussis vaccine an inactivated vaccine?

The pertussis vaccine is not an inactivated vaccine but a live attenuated vaccine, which primarily stimulates the body to produce antibodies. Once antibodies are produced, it can effectively prevent the disease pertussis. The commonly used pertussis vaccine in clinical settings is the trivalent vaccine, also known as the DTP vaccine, which can prevent pertussis, diphtheria, and tetanus—three infectious diseases caused by pathogens. It is essential to follow medical advice and complete the vaccination schedule as prescribed to achieve prevention. After vaccination, it is crucial to observe for any complications or adverse reactions.