Pertussis, a respiratory infectious disease, is recommended to be checked and treated at local formal medical institutions. Once diagnosed, the main principle is to kill the Corynebacterium diphtheriae and choose sensitive antibiotics, such as macrolide antibiotics like erythromycin, azithromycin, or clarithromycin. Additionally, symptomatic treatment should be provided, including oxygen therapy for breathing difficulties, using medications to relieve bronchial smooth muscle spasms, thinning mucus, and alleviating uncomfortable symptoms such as coughing. It is also important to drink plenty of water, rest, and maintain good hygiene.