What causes whooping cough?

Written by Li Jian Wu
Pulmonology
Updated on January 11, 2025
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Pertussis, also known as whooping cough, is a respiratory infectious disease primarily caused by the Bordetella pertussis or Corynebacterium diphtheriae bacteria. It is contagious and has a prolonged course, often leading to paroxysmal spasmodic coughing. It is commonly seen in infants and spreads through airborne droplets and close contact. The disease is generally prevented through vaccination. It has been included in the national free vaccination program, with babies receiving injections at three, four, and five months of age as part of their basic immunization, followed by a booster shot after the age of two. Once antibodies are produced, they can effectively prevent the disease.

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Written by Li Jian Wu
Pulmonology
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Is whooping cough an infectious disease?

Pertussis, also known as whooping cough, is a contagious disease that is a respiratory tract infection. It primarily spreads through airborne droplets and close daily contact. Clinically, there is a vaccine available for this condition, mainly the DTP (diphtheria, tetanus, and pertussis) vaccine. Following the vaccination schedule and developing antibodies can effectively prevent the disease. This disease has a lengthy course and can easily cause recurrent coughing episodes and persistent symptoms. It is important to correctly understand and be aware of the characteristics of its onset. If suspected, early examination and timely selection of medications for symptom control are essential, along with addressing the underlying cause.

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Written by Zeng Hai Jiang
Pediatrics
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How to determine whether it is the paroxysmal stage or the recovery stage of pertussis?

After the incubation period, typical whooping cough goes through three clinical stages. The first stage is the catarrhal stage, also called the pre-paroxysmal stage, during which the infectivity is the strongest. If treated promptly during this stage, the progress of the disease can be controlled. If the catarrhal stage is not effectively controlled, it then enters the paroxysmal stage. During the paroxysmal stage, the patient will experience episodic spasmodic coughing, with more severe episodes at night. During spasms, there will be neck vein distension, swollen and congested eyelids and face, and cyanosis of the lips. This stage can last up to two months. After the paroxysmal stage follows the convalescent stage, where the episodic spasmodic coughing gradually decreases and becomes less severe.

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Written by Zeng Hai Jiang
Pediatrics
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Is whooping cough without the crowing sound getting better?

Pertussis without a crowing sound indicates recovery. Pertussis, also known as whooping cough, is an acute respiratory infection caused by Bordetella pertussis, commonly seen in children. The progression of pertussis can be divided into three stages: The first stage is the catarrhal stage, also known as the pre-paroxysmal stage. At the early stage, the child shows symptoms similar to the common cold, followed by worsening cough. If the condition is not effectively controlled during this stage, It then progresses to the second stage, the paroxysmal stage. During the paroxysmal stage, the child exhibits characteristic episodic spasmodic coughing and crowing inhalation sounds. This period can last up to two months. Finally, it moves into the recovery stage. In the recovery stage, the frequency and severity of the episodic spasmodic cough and crowing inhalation sounds gradually alleviate. Thus, the absence of a crowing sound in whooping cough is an indication of approaching recovery.

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Written by Li Jian Wu
Pulmonology
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What causes fever in pertussis?

Pertussis, a symptom caused by the infection of Corynebacterium diphtheriae or Bordetella pertussis, facilitates the presence of these substantive pathogens in the body. These pathogens stimulate the body's temperature regulation center, leading to immune fever symptoms. This is a reaction where the body's resistance is fighting against these pathogens, causing a rise in body temperature which is considered normal. During the acute phase, symptomatic treatment should be administered. At the same time, based on the type of infectious pathogen, a sensitive antimicrobial agent should be chosen for etiological treatment. Additionally, it's important to drink plenty of fluids and maintain clean indoor air.

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Written by Li Jian Wu
Pulmonology
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How to Read Pertussis Test Results

The test for whooping cough is to see if there are any pathogens in the body. If it is confirmed that there is Bordetella pertussis, it can be determined that this disease causes spasmodic coughing, which might be prolonged and recurrent. It may also lead to fever, breathing difficulties, cyanosis of the lips, and signs of hypoxia, requiring symptomatic treatment first. At the same time, selecting macrolide antibiotics to kill the Bordetella pertussis, maintaining a good mental attitude, and ensuring that the room temperature and humidity are kept at appropriate levels are important. Attention should also be paid to the disinfection of the air. Additionally, as it is a communicable disease, isolation treatment is recommended to prevent cross-infection. It is important to adjust your mental attitude, follow the course of medication, and have regular check-ups.